Results 91 to 100 of about 10,948,837 (276)
Revista VortexThis essay is a reflection on the music of composer Morton Feldman and its significance for composers today. In particular, it traces the development of Feldman's compositional aesthetic from his early graphic works to his later complex compositions of ...
Ming Tsao
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Revista Facultad de Odontología Universidad de Antioquia, 1999 By 1993 was made the h:rst colambian health and sodal welfare amend, better Know as "Ley100". This- amend broke the old health service °utiliza The new interpretado.n ofhealth Jaws has affected the priva te medica] and odontologicalpractice.
Jaime Castro-N. +4 more
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FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
100–100–100: a new, ambitious treatment target to end the HIV and hepatitis C epidemics
The Lancet Public Health, 2022 Joshua A Barocas
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Deformable Scaffold, Manufacturing Method Thereof And Deforming, Recovery Method
, 2019 본 발명은 스캐폴드에 관한 것으로, 보다 상세하게는 형상변형이 가능한 스캐폴드, 그 제조방법 및 변형복원 방법에 관한 것이다. 이를 위해, 제1 형태를 갖는 스캐폴드(100); 스캐폴드(100)에 담지되어 제1형태와 다른 제2 형태로 스캐폴드(100)를 변형시키는 변형수단; 스캐폴드(100)에 담지되어 외부의 자력에 반응하는 자성체(20); 및 스캐폴드(100)에 담지되는 세포 또는 약물;을 포함하는 것을 특징으로 하는 형상변형이 가능한 스캐폴드가 ...
송원경 +5 more
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Precise and Miniature Parallel Robot Manipulator
, 2020 본 발명은 외형을 이루는 프레임부(100)와, 상기 프레임부(100)에 결합되며 개별적으로 작동되는 복수의 구동부(200)와, 상기 프레임부(100) 내측에 구비되고 바닥면에는 소정의 작업을 행하는 디바이스(device)가 장착되는 종말 작동체(300)와, 상기 종말 작동체(300)와 상기 복수의 구동부(200) 각각을 연결하는 링크부(400)를 포함하여 이루어지고, 상기 구동부(200) 작동에 의해 상기 링크부(400)를 구동함으로써 상기 종말 ...
이명호, 송철
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
, 1974 Folheto publicado pela Cúria Diocesana de Nova Iguaçu de 1977 a 1984 com foco nas questões políticas e sociais que afetavam a vida dos habitantes da Baixada Fluminense, a partir da perspectiva da doutrina Cristã.
Hypólito, Dom Adriano Mandarino
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