Results 201 to 210 of about 6,778,204 (293)
<i>Limosilactobacillus reuteri</i> M4-100 Mitigates the Pathogenicity of <i>Escherichia coli</i> Strain HMLN-1 in an Intestinal Epithelial Model and Modulates Host Cell Gene Expression. [PDF]
MicroorganismsAsgari B +4 more
europepmc +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Solitary rectal ulcer syndrome: MRI findings and differentiation from rectal cancer. [PDF]
Insights ImagingXie P +9 more
europepmc +1 more source
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
GAPNet: Single and multiplant leaf disease classification method based on simplified SqueezeNet for grape, apple and potato plants. [PDF]
PeerJ Comput SciÖzaras ÖN, Günay Yılmaz A.
europepmc +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source