Results 91 to 100 of about 510,536 (313)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Yield and quality of soybean seeds as affected by growing conditions [PDF]
Ratarstvo i Povrtarstvo, 2011 Effect of environmental conditions (temperatures and precipitation) on soybean yield and seed quality was examined during two years. Trials with four replications were located at experimental fields of Institute of Field and Vegetable Crops at Rimski ...
Đukić Vojin +6 more
doaj +1 more source
Character association and path analysis for yield and its related traits in finger millet (Eleusine coracana (L.) Gaertn) genotypes [PDF]
, 2017 The present investigation was conducted during Kharif, 2014 at Research Block, Department of Crop Improvement, College of Forestry, Ranichauri Campus, V.C.S.G. Uttarakhand University of Horticulture and Forestry.
Bhatt, Arun +2 more
core +2 more sources
PLoS ONE, 2018 Kernel morphology characteristics of wheat are complex and quantitatively inherited. A doubled haploid (DH) population of the cross RL4452/‘AC Domain’ was used to study the genetic basis of seed shape.
A. L. Cabral +5 more
semanticscholar +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Effect of Plant Density on Yield and Yield Seed Components of Rapeseed (Brassica napus) Cultivars [PDF]
Ikufīziyuluzhī-i Giyāhān-i Zirā̒ī, 2013 To study the effects of different plant density on seed yield and yield components of three spring rapeseed cultivars a factorial experiment based on a Randomized Complete Block Design with three replications and 9 treatments was carried out during 2011 ...
M. Matinfar +4 more
doaj
SEVERAL ELEMENTS OF SEED PRODUCTIVITY IN CUCUMBER CULTIVARS BRED AT VNIISSOK
Овощи России, 2017 Routine breeding work for cucumber cultivar and hybrid maintenance and their multiplication is carried out at Laboratory of Cucumber and Gourd Breeding and Seed Production, VNIISSOK.
I. B. Korotseva, L. A. Kochetkova
doaj +1 more source
Forests, 2019 This paper examines the effects of seed size and the depth of sand burial on seed germination and seedling development for Pinus thunbergii. Parl. Seeds from 20- to 30-year old trees grown in the coastal area of Yantai were divided into three size ...
Peili Mao +4 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source