Results 41 to 50 of about 367,991 (224)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
miR-103 Functions as a Tumor Suppressor by Directly Targeting Programmed Cell Death 10 in NSCLC
Oncology Research, 2018 Non-small cell lung cancer (NSCLC) accounts for about 85% of all lung cancer cases. Absence of miR-103 has recently been identified to be associated with metastatic capacity of primary lung tumors.
Dong Yang +3 more
semanticscholar +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Low-dose oral flecainide provocation test for Brugada syndrome: a case series
The Egyptian Heart JournalBackground Brugada syndrome is a rare, inherited cardiac disorder that predisposes individuals to life-threatening ventricular arrhythmias, often leading to sudden cardiac arrest.
Xuan Nguyen Thanh +7 more
doaj +1 more source
Saudi Journal of Emergency MedicineIntroduction: Disasters have existed for many ages and although they are known to threaten health, there is still lack of evidence regarding the effectiveness of health disaster response interventions.
Sofie Pauwels +2 more
doaj +1 more source
Micromachines, 2015 The high throughput preparation of emulsions with high internal volume fractions is important for many different applications, e.g., drug delivery. However, most emulsification techniques reach only low internal volume fractions and need stable flow ...
Friedrich Schuler +3 more
doaj +1 more source
Comparative analysis of surgical interventions for postoperative ventral hernia in obese patients
Medičnì Perspektivi, 2021 The problem of surgical treatment of postoperative ventral hernias remains relevant today. Currently, a large number of methods of surgical interventions for hernias of the anterior abdominal wall have been proposed, the variety of which requires ...
B.S. Kravchenko +3 more
doaj +1 more source
AntagomiR-103 and -107 Treatment Affects Cardiac Function and Metabolism
Molecular Therapy: Nucleic Acids, 2018 MicroRNA-103/107 regulate systemic glucose metabolism and insulin sensitivity. For this reason, inhibitory strategies for these microRNAs are currently being tested in clinical trials.
Monika Rech +15 more
semanticscholar +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The Indian Journal of Agricultural Sciences, 2014 The objective of our study was to know the differences in expression of total protein, total phenol, peroxidase and polyphenoloxidase activities in self-defense in plant tissues against rice blast diseases. The activities of these compounds were studied
P D THONGBAM +3 more
doaj +1 more source