Results 181 to 190 of about 740,893 (339)

Spatiotemporal Control Over Protein Release from Artificial Cells via a Light‐Activatable Protease

Advanced Biology, EarlyView.
Stimulus‐responsive protein release is essential for intercellular communication. Mimicking this functionality in artificial cells is promising to study the working principles of cellular signaling. Herein, an engineered light‐activatable protease is implemented in a coacervate‐based artificial cell platform to establish user‐defined spatiotemporal ...
Arjan Hazegh Nikroo, Wiggert J. Altenburg, Thijs W. van Veldhuisen, Luc Brunsveld, Jan C. M. van Hest   +4 more
wiley   +1 more source

The sustainability of health interventions implemented in Africa: an updated systematic review on evidence and future research perspectives. [PDF]

Implement Sci Commun
Nwaozuru U, Murphy P, Richard A, Obiezu-Umeh C, Shato T, Obionu I, Gbajabiamila T, Oladele D, Mason S, Takenaka BP, Blessing LA, Engelhart A, Nkengasong S, Chinaemerem ID, Anikamadu O, Adeoti E, Patel P, Ojo T, Olusanya O, Shelley D, Airhihenbuwa C, Ogedegbe G, Ezechi O, Iwelunmor J.   +23 more
europepmc   +1 more source

Light‐Triggered Protease‐Mediated Release of Actin‐Bound Cargo from Synthetic Cells

Advanced Biology, EarlyView.
TEV Prtoease‐mediated Releasable Actin‐binding Protein (TRAP) is a protein‐based platform consisting of a cargo tightly bound to reconstituted actin networks in synthetic cells which can be proteolyticly released from the bound actin, followed by its secretion through membrane translocation mediated by a cell‐penetrating peptide.
Mousumi Akter, Hossein Moghimianavval, Gary D. Luker, Allen P. Liu   +3 more
wiley   +1 more source

Bridging the gap in sustainable radiography: insights from five countries in Asia and Africa. [PDF]

BMC Health Serv Res
Abuzaid M, Almuqbil N, Emery CV, Elshami W, Ibham M, Alsubaie N, Hamd Z, Aljamal M.   +7 more
europepmc   +1 more source

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Advanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim, Kanghoon Choi, Amy Lin, Jungkyu Kim   +3 more
wiley   +1 more source

The need for sustainable innovation in an era of political uncertainty. [PDF]

Eur J Public Health
Albreht T, Marchandise C, Keskimäki I, Barnhoorn F.   +3 more
europepmc   +1 more source

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

Advanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang, Lijuan Zhang, Jiaorong Tan, Fei Li, Yishan Jin, Limei He, Xin Yang   +6 more
wiley   +1 more source

Salt stress mitigation and improvement in fruit nutritional characteristics of tomato plants: New opportunities from the exploitation of a halotorelant Agrobacterium strain

Plant Stress
Soil salinity is considered one of the most limiting factors in large agricultural areas, and tomato (Solanum lycopersicum L.) is highly sensitive to this abiotic stress, which exacerbates under drought.
Silvia Potestio, Gianluigi Giannelli, Francesca Degola, Teofilo Vamerali, Rosaria Fragni, Emanuela Cocconi, Luca Sandei, Giovanna Visioli   +7 more
doaj  

Promoting the Sustainability of Suicide Prevention Projects in Switzerland. [PDF]

Public Health Rev
Werdin S, Hollenstein E, Wyss K.
europepmc   +1 more source

Regulating Protein Immobilization During Cell‐Free Protein Synthesis in Hyaluronan Microgels

Advanced Biology, EarlyView.
Bifunctional microgels carrying a linear DNA template and Ni2+‐activated NTA moieties are used as platform for cell‐free protein synthesis and in situ protein immobilization. By varying the concentration of NTA moieties in the microgels, the amount of GFP‐His immobilized inside the microgel and released to the microgel environment can be regulated ...
Anika Kaufmann, Kateryna Ivanova, Julian Thiele   +2 more
wiley   +1 more source