Results 21 to 30 of about 384,780 (261)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Fruit and vegetable intake among Nigerian University students: patterns, preferences, and influencing factors

Open Agriculture
Adequate consumption of fruits and vegetables is globally recognized as a cornerstone of healthy living and a critical strategy for preventing micronutrient deficiencies and non-communicable diseases.
Solaja Sodipe O., Bamiro Olasunkanmi M., Ayeni Matthew D., Mohammed Glory   +3 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Sustainability starts with the consumer: How green consumption shapes business model transformation a COM-B analysis of green purchase behavior in Vietnam’s agriculture

Sustainable Futures
This study is motivated by the need to align national sustainability goals with real consumer behavior by identifying the barriers that block green purchase follow-through.
Ta Thi Nguyet Trang, Pham Thi Hanh Lan, Phan Quynh Anh, Khanh Bao Nguyen   +3 more
doaj   +1 more source

The Association Between Fast-Food Consumption and Physical Activity with Overweight Occurrence at School Among 9-11-Year-Old Children in Cakung Payangan Bekasi

Jurnal Ilmu Kesehatan Masyarakat, 2020
Overweight occurs because of excessive energy intake stored in the form of fat tissue. The national prevalence of overweight and obesity among children aged 5­-12 years old was 10.8% and 8.8%, respectively.
Iin Fatmawati, Andreas Wisnu Pradhan, Firlia Ayu Arini   +2 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Insights and learnings from the use of design thinking for digital agricultural innovation design

Advancements in Agricultural Development
This research contributes to the growing discourse on participatory approaches for digital agricultural innovation design. Specifically, it details practical insights and learnings from applying the first three phases of a design thinking approach to the
Karen McGrath, Jim Kinsella, Aine Regan, Tomas Russell   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source