Results 41 to 50 of about 1,008,506 (285)

SACRIFICIAL ANODE CATHODIC PROTECTION OF LOW CARBON STEEL IN SEA WATER

open access: yesJournal of Engineering, 2006
Cathodic protection is a corrosion-prevention technique which uses the electrochemical properties of metals to insure that the structure to be protected becomes the cathode of an electrolytic cell Laboratory evaluation was conducted on zinc electrode ...
Aprael S. Yaro, Khalid W. Hameed
doaj   +1 more source

Employees’ Commitment to Sustainable Development Goals Approach [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2023
Sustainable development is a goal that every citizen, every organization, and every government must consider. Therefore, an SDG12: Responsible Consumption and Production analysis must be carried out at the individual and organizational levels. The main
Florin-Aurelian Birchi   +2 more
doaj  

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Assessing environmental impacts in batik production through life cycle assessment [PDF]

open access: yesBIO Web of Conferences
This study investigates a small and medium enterprise (SME) in the batik industry located in Pekalongan, Indonesia. The enterprise faces significant challenges due to pollution generated by its production waste, raising serious environmental concerns ...
Asih Hayati Mukti   +2 more
doaj   +1 more source

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini   +11 more
wiley   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

Comparative assessment of performance, combustion, and emission of compression ignition engine fuelled with different generations of biodiesel

open access: yesInternational Journal of Sustainable Engineering, 2021
In the present research work, the performance, combustion and emission characteristics of compression ignition engine fuelled 22 different biodiesels categorised as (first, second, third generation, waste oil, and animal oil) biodiesel (B100) are ...
Vishal Sharad Kumbhar   +3 more
doaj   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Modeling the Factors That Determine Sustainable Development Goal 12 in University Students

open access: yesEducation Sciences
SDG12 is one of the top three Sustainable Development Goals that require more urgent action. Hence, this work aims to develop and validate a conceptual model that measures the main factors which may influence university students’ sustainable consumption ...
Monica Martinez Gomez   +2 more
doaj   +1 more source

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