Results 51 to 60 of about 377,607 (275)

Responsible consumption and production as 12th sustainable development goal: a commentary on Pakistani students green entrepreneurship orientation [PDF]

Journal of Responsible Production and Consumption
PurposeDespite the discussion among scholars on green entrepreneurship and sustainable development, little is known regarding the role of responsible consumption and production implementation, which is the 12th goal among the sustainable development ...
Muhammad Murad
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Sustainable Fashion Principle-Based Multifunctional Clothing [PDF]

E3S Web of Conferences
The rapid growth of the fashion industry has intensified environmental pressures, including excessive textile waste, high resource consumption, and increasing carbon emissions.
Listiani Sri, Suryawati, Zahra E. Lutfia
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Purchase intention of Muslim consumers on TikTok live stream: Assessing the role of trust, reliability, and TikTok marketing activitie [PDF]

International Journal of Data and Network Science
This study explores the impact of TikTok marketing activities in stimulating consumer purchasing intention with trust and reliability during live streaming sessions for Muslim apparel.
Usep Suhud, Mamoon Allan, Wong Chee Hoo, Juliana Juliana   +3 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Advancing Sustainable Development Through Circularity Metrics: A Comprehensive Indicator Framework for Assessing Progress on SDG 12 Across Sectoral Drivers

Resources
This study provides an integrated assessment of progress toward Sustainable Development Goal 12 (Responsible Consumption and Production) by applying a multivariate, indicator-based framework to a comprehensive set of EU-27 performance metrics.
Ionela Gavrila-Paven, Ramona Giurea, Elena Cristina Rada   +2 more
doaj   +1 more source

Association between the incidence of hypertension and alcohol consumption pattern and the alcohol flushing response: A 12-year follow-up study

Alcohol, 2020
Alcohol consumption is associated with hypertension, and this association depends on the alcohol consumption pattern and alcohol flushing response. In this 12-year follow-up study, we investigated the relationship between the alcohol consumption pattern and incidence of hypertension in the Korean population.We analyzed 1,366 Korean participants in the ...
Min-Gyu Yoo, Yoo Jeong Lee, Han Byul Jang, Hyo-Jin Kim, Hye-Ja Lee, Sang Ick Park   +5 more
openaire   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Regional dynamics of precision agriculture adoption and knowledge transfer: Insights from Georgia extension agents

Advancements in Agricultural Development
The Cooperative Extension System plays a vital role in disseminating innovative knowledge from the University to public decision makers. However, there is a lack of studies on the dynamics of knowledge transfer from Extension agents to farmers ...
Ginger Orton, Chin-Ling Lee
doaj   +1 more source