Results 161 to 170 of about 273,277 (277)

Pulmonary Delivery of siRNA Anti‐TNFα‐loaded Lipid Nanoparticles for Rapid Recovery in Murine Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
In a murine model of acute lung injury, pulmonary administration of lipid nanoparticles carrying TNFα siRNA enables targeted delivery to immune cells. The study emphasises the importance of optimizing LNP distribution and delivery timing to improve therapeutic outcomes and develop emergency therapies for lung hyperinflammation.
Qinglin Wang, Jihana Achour, Laila Emam, Younes Louaguenouni, Catherine Cailleau, Françoise Mercier‐Nomé, Séverine Domenichini, Claudine Delomenie, Sezen Gul, Juliette Vergnaud, Nicolas Tsapis, Arnaud Mansart, Djillali Annane, Francois Fay, Elias Fattal   +14 more
wiley   +1 more source

Role of Field Epidemiology in Environmental and Climate Change-Related Health Incidents in Wales: A Qualitative Analysis Through Expert Interviews. [PDF]

Int J Environ Res Public Health
Sonmez OF, Behbod B, Roberts C, Barracchia M, Baghinyan A, Indra L, Czabanowska K.   +6 more
europepmc   +1 more source

Leveraging Java Programming for Climate Action: Developing a Solution to Address Air Quality and Sustainable Development Goal 13

M.R. Aziz, Noor Ul Amin, Prashanth Nair Kumaran, Ahmed Hassan Ahmed, Salman Zaman, Nurul Syaziah binti Abdul Kareem, Chao Qin   +6 more
openalex   +1 more source

Biologically Active Implants Prevent Mortality in a Mouse Sepsis Model

Advanced Healthcare Materials, EarlyView.
A modular, triple‐action titanium implant is developed to prevent implant‐associated infections by repelling bacteria, killing pathogens, and enhancing tissue integration. Coatings with phage cocktails targeting P. aeruginosa and S. aureus show significant bacterial reduction and improved survival in a mouse sepsis model.
Martin Stark, Fereshteh Bayat, Sara Rahmani, Mathura Thirugnanasampanthar, Taylor Kramer, Elise Schwarz, David Wilson, Jeffrey I. Weitz, Zeinab Hosseinidoust, Tohid F. Didar   +9 more
wiley   +1 more source

Cool Solutions in Hot Times: The Case for Digital Health in Heatwave Action Plans. [PDF]

Online J Public Health Inform
Loureiro MD, Jennings N, Lawrance E, Ferreira-Santos D, Neves AL.   +4 more
europepmc   +1 more source

From Values to Climate Action: The Impact of Green Self-Efficacy on Pro-Environmental Behaviour in Greater Jakarta’s Higher Education Zillenials (SDG 13 View)

Maria Grace Herlina, Karto Iskandar, Dewi Dewi   +2 more
openalex   +1 more source

Multiscale Profiling of Nanoscale Metal‐Organic Framework Biocompatibility and Immune Interactions

Advanced Healthcare Materials, EarlyView.
A multi‐scale, hierarchical ‘Safety‐by‐Design’ pipeline combining machine learning, ex vivo human blood assays, and in vivo models enables the systematic immunotoxicity and biocompatibility profiling of nanoscale metal‐organic frameworks, accelerating their safe clinical translation. Abstract The clinical translation of metal‐organic frameworks (MOFs) –
Yunhui Zhuang, Bárbara B. Mendes, Dhruv Menon, Jhenifer Oliveira, Xu Chen, Fatma Demir Duman, João Conniot, Sergio Mercado, Xiewen Liu, Shi‐Yuan Zhang, João Conde, Rachel E. Hewitt, David Fairen‐Jimenez   +12 more
wiley   +1 more source

Addressing the overlooked frontier in AMR research and surveillance. [PDF]

Front Public Health
Thakur R, Dhar H, Wozniak TM, Mathew S.
europepmc   +1 more source

OVERPOPULATION-A CHALLENGE TO SUSTAINABLE DEVELOPMENT GOALS: SGD 6 (CLEAN WATER AND SANITATION), SGD 7 (AFFORDABLE AND CLEAN ENERGY), SDG 11(SUSTAINABLE CITIES AND COMMUNITIES) AND SDG 13 (CLIMATE ACTION) AND INTEGRATION OF EIA IN DESIGNING MITIGATION FRAMEWORKS

openalex   +1 more source

Suppressing t(4;11) Acute Leukemia by Lipopolymer Nanoparticle Delivery of siRNA Targeting KMT2A::AFF1 with Enhanced Extrahepatic Delivery

Advanced Healthcare Materials, EarlyView.
This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah, Remant KC, Amarnath Praphakar Rajendran, Saba Abbasi Dezfouli, Cezary Kucharski, Xiaoyan Jiang, Spencer B. Gibson, Joseph Brandwein, Olaf Heidenreich, Hasan Uludağ   +9 more
wiley   +1 more source