Results 221 to 230 of about 35,774 (283)

Skeletal muscle myosin heavy chain fragmentation following exercise may be linked to post‐exercise inflammation and remodelling

Experimental Physiology, EarlyView.
Abstract The purpose of this exploratory investigation was to determine if acute post‐exercise skeletal muscle myosin heavy chain fragmentation (MyHCfrag) coincides with alterations in molecular chaperones and proteolytic enzymes, select markers of mammalian target of rapamycin complex 1 (mTORC1) signalling, and/or specific gene expression signatures ...
Dakota R. Tiede, Diego Bittencourt, J. Max Michel, Daniel L. Plotkin, Madison L. Mattingly, Derick A. Anglin, Christopher G. Vann, Zachary A. Graham, Timothy J. Broderick, Marcas M. Bamman, Michael D. Roberts   +10 more
wiley   +1 more source

Biocompatible SABRE Hyperpolarization of [1-¹³C]Ketoleucine for Cellular Metabolic Flux Sensing. [PDF]

Chemistry
TomHon P, Gyesi J, Abdurraheem A, McBride S, Samoilenko A, Oladun C, Curran E, Pike M, Welch SD, Scofield S, Goodson BM, Sadagurski M, Theis T, Chekmenev EY.   +13 more
europepmc   +1 more source

Co‐ingesting whey protein with dual‐source carbohydrate enhances amino acid availability without compromising post‐exercise liver glycogen resynthesis

The Journal of Physiology, EarlyView.
Abstract figure legend Graphical overview of the experimental study. The upper‐left panel presents the research question, and the bottom‐left panel provides a schematic overview of the experimental design. The right‐hand panel depicts repetitive spectral data obtained by magnetic resonance spectroscopy, liver glycogen content during the 5 h post ...
Sophie C. Hannon, James McStravick, Libby Henthorn, Stephen J. Bawden, Jonathan C. Y. Tang, Rachel Dunn, Ryosuke Makino, Kenneth Smith, Javier T. Gonzalez, Nathan Hodson, James P. Morton, Aneurin J. Kennerley, Mark A. Hearris   +12 more
wiley   +1 more source

Antioxidant supplementation blunts the proteome response to 3 weeks of sprint interval training preferentially in human type 2 muscle fibres

The Journal of Physiology, EarlyView.
Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma, Marta Murgia, Sigitas Kamandulis, Stefano Gastaldello, Marius Brazaitis, Audrius Snieckus, Nerijus Eimantas, Mati Pääsuke, Sebastian Edman, William Apro, Daniel C. Andersson, Håkan Westerblad, Tomas Venckunas   +12 more
wiley   +1 more source

Carbohydrate intake of 10 g/kg body mass rapidly replenishes liver, but not muscle glycogen contents, during 12 h of post‐exercise recovery in well‐trained cyclists

The Journal of Physiology, EarlyView.
Abstract figure legend Exhaustive cycling exercise substantially reduces liver and muscle glycogen stores. During 12 h of post‐exercise recovery without carbohydrate intake, glycogen stores remain depleted. In contrast, when carbohydrate is consumed at 10 g/kg body mass (BM), provided during the first 6 h as sucrose beverages (1.2 g/kg BM/h), liver ...
Cas J. Fuchs, Pandichelvam Veeraiah, Wesley J.H. Hermans, Bente Brauwers, Rick Voncken, Kim Brouwers, Heather L. Petrick, Floris K. Hendriks, Julia L.M. Bels, Job van den Hurk, Jil Weber, Joan M. Senden, Fiona E. Smith, Peter E. Thelwall, Jeanine J. Prompers, Luc J.C. van Loon   +15 more
wiley   +1 more source

Low‐Head Dam Removal Restores Biofilm Structure but Not Function in a Temperate Stream

International Review of Hydrobiology, Volume 111, Issue 1, June 2026.
ABSTRACT Barrier removal is a common stream restoration practice aimed at restoring longitudinal connectivity, yet its effects on biofilm structure and function, through alteration of near‐bed hydrodynamics, remain unclear. Using a space‐for‐time substitution approach, we assessed how the presence and removal of a low‐head dam affect biofilm structure ...
Julia Pasqualini, Christine Anlanger, Clara Mendoza‐Lera, Patrick Fink, Andreas Lorke, Markus Weitere, Ulisses Nunes da Rocha, Kay Knöller, Travis Meador, Mario Brauns   +9 more
wiley   +1 more source

In Vitro Metabolism and Analytical Characterization of SLU‐PP‐332 and SLU‐PP‐915: Novel Pan‐ERR Agonists With Doping Potential

Rapid Communications in Mass Spectrometry, Volume 40, Issue 8, 30 April 2026.
ABSTRACT Rationale Estrogen‐related receptor (ERR) agonists such as the drug candidates SLU‐PP‐332 and SLU‐PP‐915 are currently being investigated as exercise mimetics, given their ability to trigger human physiological processes similar to those initiated by actual physical activity.
Tristan Möller, Oliver Krug, Mario Thevis   +2 more
wiley   +1 more source

Quantitative decoding of coupled carbon and energy metabolism in Pseudomonas putida for lignin carbon utilization. [PDF]

Commun Biol
Zhou N, Wilkes RA, Chen X, Teitel KP, Belgrave JA, Beckham GT, Werner AZ, Yu Y, Aristilde L.   +8 more
europepmc   +1 more source

Increasing Infusion Times of Hyperpolarized [1‐13C]Pyruvate in a Mouse Brain Maintain Lactate Generation and Approach Pseudo‐Steady State Metabolism

Magnetic Resonance in Medicine, Volume 95, Issue 4, Page 2254-2265, April 2026.
ABSTRACT Purpose To investigate whether varying delivery times of hyperpolarized [1‐13C]pyruvate, enabled by the increased apparent T1 dissolved in deuterium oxide (D2O), affects the observed kinetics of glycolytic brain metabolism in vivo. Methods Eighteen healthy mice were injected with 300 μL of hyperpolarized [1‐13C]pyruvate dissolved in D2O at ...
Paola Porcari, Vesselin Miloushev, Saket Patel, Thasin Peyear, Marjan Berishaj, Kayvan R. Keshari   +5 more
wiley   +1 more source

Non-invasive visualisation of long-lasting brain metabolic alterations in murine pseudo-infection model using parahydrogen-polarised [1-¹³C] pyruvate MRI. [PDF]

Discov Nano
Tomiyama H, Yamasaki M, Isagawa T, Takeda N, Hashimoto T, Hirata H, Matsumoto S.   +6 more
europepmc   +1 more source