Results 151 to 160 of about 281,059 (296)

Feasibility of co-polarizing ¹³C-pyruvate and ¹³C-tert-butanol for simultaneous metabolic and perfusion imaging. [PDF]

Npj Imaging
Dos Santos K, Calos SR, Dou Q, Takahashi AM, Tsai LL, Grant AK, Yen YF.   +6 more
europepmc   +1 more source

Bipolar Covalent Organic Frameworks Crafting Core–Shell Heterostructured Cathode for High–Performance Lithium–Organic Batteries

Advanced Science, EarlyView.
A bipolar CNT@COF core–shell heterostructure cathode constructed via synergistic molecular and microstructural engineering enables rapid electron/ion transport and efficient utilization of electroactive groups for high–performance lithium–organic batteries. ABSTRACT Covalent organic frameworks (COFs) with tunable molecular structures and ordered porous
Yalong Jiang, Nan Jiang, Yu Dou, Zixuan Chen, Yunhai Zhu, Long Chen, Yingkui Yang   +6 more
wiley   +1 more source

A commensal protozoan exacerbates acetaminophen-induced liver injury by producing free sphingosine. [PDF]

Gut Microbes
Yan X, Shen Y, Sun Q, Zhu X, Chen Q, Liao L, Zhou Y, Cheng W, Shi Z, Liu Z, Wei Y, Liu X, Wang Y, Kou Y.   +13 more
europepmc   +1 more source

Discovery of a Potent Fluorescence Polarization Probe for Identifying USP1 Allosteric Inhibitors

Advanced Science, EarlyView.
This study presents the first ubiquitin‐specific protease 1 (USP1) allosteric fluoroprobe and fluorescence polarization assay, enabling the differentiation of allosteric and catalytic site inhibitors. Further, a novel class of tetrahydroisoquinoline‐based USP1 inhibitors is designed, with compound 14a (USP1 IC50 = 29.9 nM) showing strong selectivity ...
Jiawei Cheng, Peipei Wang, Pengfei Wang, Jiamin Wang, Baiyang Li, Daqing Fang, Jian He, Xiaobei Hu, Weijuan Kan, Yubo Zhou, Chunpu Li, Jia Li, Hong Liu   +12 more
wiley   +1 more source

A Triple-Resonance NMR Strategy for the Selective Detection of NAD⁺ and NADH Derived from a ¹³C/¹⁵N-Nicotinamide Riboside Probe in the Liver Extracts of Mice. [PDF]

Sensors (Basel)
Shimada H, Shinohara Y, Uto Y, Yamada H.
europepmc   +1 more source

Tyrosinase Driven‐Intracellular Polymerization of a Porphyrin Derivative Induced Immunogenic Death of Melanoma Cells and Strengthened Photodynamic Therapy

Advanced Science, EarlyView.
This study uses tyrosinase, which is highly expressed in melanoma, to drive porphyrins to polymerize and self‐assemble within tumor cells to form retented microstructures. This process induces immunogenic death and activates immune responses (M1 macrophages, dendritic cells, CD8+T cells), turning “cold” tumors into “hot” tumors.
Mian Tang, Junteng Qiu, Yunfeng Lu, Yahui Song, Xinyu Zhou, Tianshun Duan, Xuanqi Peng, Caixia Yin, Cheng Gao, Ruibing Wang   +9 more
wiley   +1 more source

Mechanochemically assembled organometallic complexes: a mechanistic study. [PDF]

Chem Sci
Hamdouna L, Pisanò G, Rankin AGM, Trébosc J, Falivene L, Ritacco I, Devos O, Delevoye L, Roussel P, Caporaso L, Cavallo L, Nolan SP, Lafon O, Cazin CSJ.   +13 more
europepmc   +1 more source

Cucurbit[8]Uril Achieved Single‐Molecule Chiral Transfer to Supramolecular Circularly Polarized Luminescence

Advanced Science, EarlyView.
A single‐molecule cascade supramolecular system comprising L/D‐FPy, CB[8], and SC4AD serves as an efficient light‐harvesting platform. It facilitates cascade energy transfer and chiral transfer to acceptor dyes. Co‐assembly with a PVA matrix produces a multicolor solid film that exhibits enhanced luminescence dissymmetry factors (glum), enabling ...
Yongxue Li, Jie Wu, Weiheng Zhang, Hengzhi Zhang, Wei‐Lei Zhou, Yu Liu   +5 more
wiley   +1 more source

Development and First-in-Human Translation of Hyperpolarized [1-¹³C]Alpha-Ketoglutarate MR Spectroscopy in the Brain. [PDF]

Sensors (Basel)
Kim Y, Dang D, Slater J, Riselli A, Hong D, Gordon JW, Chang SM, Li Y, Villanueva-Meyer JE, Autry AW, Escobar E, Andosca S, Chen HY, Tan CT, Suszczynski C, Maddali S, Bok RA, Vigneron DB.   +17 more
europepmc   +1 more source

Spatially Separated Redox Centers in One‐Dimensional Sp2‐Carbon Covalent Organic Frameworks Enable Synergistic Photocatalytic Palladium Recovery and Bisphenol A Mineralization

Advanced Science, EarlyView.
A one‐dimensional sp2‐carbon covalent organic framework with spatially segregated redox centers integrates a dual photosensitizing system and a cationic interface for synergistic photocatalysis. The material achieves exceptional palladium recovery (1749 mg g−1) and bisphenol A mineralization (0.1710 min−1) without sacrificial agents, demonstrating ...
Yi‐Ru Chen, Jing‐Yi Li, Yao Xiao, Dan Zhong, Lu Zhang, Yu‐Ting Xie, Xiu Wang, Yibao Li, Wei‐Rong Cui, Jian‐Ding Qiu   +9 more
wiley   +1 more source