Results 121 to 130 of about 900,684 (249)

Ultrasound‐Assisted H2 Transmitter Enables Hydrogen‐Gene Therapy to Prevent Anesthesia/Surgery‐Induced Cognitive Impairment

Advanced Science, EarlyView.
Postoperative cognitive dysfunction (POCD) remains a challenge with no effective treatments. This study introduces a novel hydrogen‐gene therapy strategy, combining focused ultrasound and siRNA delivery via hydrogen emitters, to repair neuroinflammation in a precise and controlled manner.
Ruonan Zhan, Yan Fang, Chuyun Lou, Nan Chen, Xuan Mo, Bo Jiao, Mengke Liu, Yangxi Zhao, Weichen Xu, Huixiong Xu, Haohao Yin, Yi Zhang   +11 more
wiley   +1 more source

Catheter Injectable Multifunctional Biomaterial for the Treatment of Infected Enterocutaneous Fistulas

Advanced Science, EarlyView.
A multi‐functional shear‐thinning hydrogel is engineered to treat enterocutaneous fistulas. This hydrogel can resist external pressures allowing it to remain within the fistula tract and is shown to have significant antimicrobial, pro‐healing, and anti‐inflammatory properties, which were validated in in vitro and in vivo experiments.
Jinjoo Kim, Zefu Zhang, Hassan Albadawi, Hyeongseop Keum, Joseph L. Mayer, Erin H. Graf, Rahmi Oklu   +6 more
wiley   +1 more source

Enhancing Grasping Function with a Thermoresponsive Ionogel Adhesive Glove for Patients with Rheumatic Diseases

Advanced Science, EarlyView.
This study presents a novel portable grasp‐assist glove, weighing only 47 g. The glove integrates smart adhesive pads and a hands‐free control interface based on IMU, designed to aid rheumatic patients with impaired hand function. The system enables switchable adhesion with independent control and detection of user release intent.
Shiqiang Wang, Shiqing Liu, Jingfeng Zhang, Zhouyang Yu, Yifan Shao, Cong Zhao, Jiahong Ma, Xin Fu, Mengqi Yang, Lie Chen, Mingjie Liu, Li Wen   +11 more
wiley   +1 more source

The Latest Advances in Mechanically Robust Self‐Healing Polyurea Based on Dynamic Chemistry

Advanced Science, EarlyView.
Solving the contradiction between strength, toughness, and self‐healing properties is extremely important to realize the breakthrough of polyurea applications. This review summarizes and discusses common strategies for the preparation of high‐performance and self‐healing polyurea materials based on dynamic chemistry, providing molecular‐level insights ...
Yujia Hao, Guangming Zhu
wiley   +1 more source

A Hollow Shell‐Lattice Soft Robot in Flexible Pipelines with Flowing Fluids

Advanced Science, EarlyView.
This study proposes a novel shell‐lattice robot with hollow bodies, capable of crawling through pipes with flowing fluids of high velocities and viscosities and mixed with impurities. The robot also features capabilities of crawling with high payloads, in curved pipes, and unthethered crawling. These unique properties make this robot high promising for
Di Guo, Yiqiang Wang, Zhan Kang
wiley   +1 more source

Reprogramming the Tumor Immune Microenvironment with ICAM‐1‐Targeted Antibody‒Drug Conjugates and B7‐H3‐CD3 Bispecific Antibodies

Advanced Science, EarlyView.
Reprogramming the tumor immune microenvironment is crucial for transforming immune “cold” tumors into “hot” inflammatory tumors. The investigation reveals that the combination of ICAM‐1‐Dxd with B7‐H3‐CD3 bispecific antibodies not only demonstrates significant inhibitory effects on tumor growth and metastasis but also plays a vital role in ...
Shoubing Zhou, Mengyu Hong, Dan Zhao, Wenyu Li, Xiaolong Yuan, Yinghong Wang, Hualong Li, Yang Yang, Tengchuan Jin, Jing Pan   +9 more
wiley   +1 more source

Economic impacts and nutritional outcomes of the 2017 floods in Bangladeshi Shodagor fishing families

American Journal of Human Biology, Volume 35, Issue 1, January 2023., 2023
Abstract Objectives As climate change continues to increase the frequency and severity of flooding in Bangladesh and globally, it becomes increasingly critical to understand the pathways through which flooding influences health outcomes, particularly in lower‐income and subsistence‐based communities.
Kathrine E. Starkweather, Monica H. Keith, Fatema tuz Zohora, Nurul Alam   +3 more
wiley   +1 more source

Simultaneous Reversal of T Lymphocytes and Cancer Cells Metabolism Via a Biomimetic Heavy‐Atom‐Free Photosensitizers‐Based Combination Therapies to Boost Cancer Photoimmunotherapy

Advanced Science, EarlyView.
This work develops a cyanine dye named Cy‐BF and encapsulates it with phospholipids and platelet exosome vesicles to create CHL. Characterized by high phototoxicity, low dark toxicity, and enhanced tumor targeting, CHL demonstrates aggregation‐induced broadening of absorption spectra and NIR‐activated photothermal therapy and type I photodynamic ...
Yongjian Zhang, Xiaohong Wu, Kaiyuan Wang, Yaohan Tang, Xiuxin Lu, Fusheng Sun, Hua Tang, Xiaoyuan Chen, Shipeng Ning   +8 more
wiley   +1 more source

Multifunctional Conductive Nanofibers for Self‐Powered Glucose Biosensors

Advanced Science, EarlyView.
This work develops a novel self‐powered glucose biosensor using polycaprolactone/polypyrrole/graphene oxide (PCL/PPy/GO) nanofibers integrated with a triboelectric nanogenerator. The system achieves high glucose detection sensitivity and generates 63 V from motion, combining robust mechanical strength with eco‐friendly energy harvesting.
Seda Gungordu Er, Rameesh Bulathsinghala, Selvinaz Burcu Kizilates, Bing Li, Rucchi Ryan, Tanveer A. Tabish, Ishara Dharmasena, Mohan Edirisinghe   +7 more
wiley   +1 more source

Mechanically Robust Mesoporous UiO‐66‐NH2/Nanofibrous Aerogel for Organophosphonates Detoxification

Advanced Science, EarlyView.
A high‐surface‐area (900 m2 g−1), ultra‐resilient (40 kPa) metal‐organic framework (MOF)‐polyacrylonitrile (PAN)/polyvinylpyrrolidone (PVP) nanofibrous aerogel (NFA) sponge with mesoporous UiO‐66‐NH₂ enables ultrafast organophosphonate (OP) absorption and detoxification, cutting degradation time to just 3 min—offering a game‐changing solution for ...
Mai O. Abdelmigeed, Muhammed Ziauddin Ahmad Ebrahim, Vahid Rahmanian, John J. Mahle, Gregory W. Peterson, Saad A. Khan, Gregory N. Parsons   +6 more
wiley   +1 more source