Results 111 to 120 of about 7,153,567 (281)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Large-diameter astromast development [PDF]

open access: yes
The 15-m-long by 0.75-diameter deployable supermast was delivered. The performance characteristics, design parameters, and developmental work associated with this mast are described.
Finley, L. A.
core   +1 more source

Charakterystyka etiologiczna udarów mózgu leczonych w Klinice Neurologii UM w Białymstoku z analizą czynników ryzyka

open access: yesAktualności Neurologiczne, 2010
Wstęp: W przeprowadzonych w Polsce badaniach epidemiologicznych stwierdzono utrzymujący się od kilkunastu lat wysoki współczynnik zapadalności na pierwszy w życiu udar mózgu, wzrastający wykładniczo z wiekiem oraz połączony z wciąż dużą śmiertelnością ...
Anna Syta-Krzyżanowska   +2 more
doaj  

The agriculture specialization through the lens of PESTLE analysis

open access: yesOpen Agriculture
Economic specialization and diversification have long been central themes in spatial development studies. This article aims to evaluate the role of state policy in shaping the specialization of agricultural organizations (farms), using evidence from ...
Khachatryan Liana   +6 more
doaj   +1 more source

Borderline Personality Disorder: Emerging Symptoms, Evolving Therapies, and the Role of Physical Activity in Treatment

open access: yesQuality in Sport
Background: Borderline Personality Disorder (BPD) is a complex and heterogeneous mental health condition, traditionally characterized by emotional dysregulation, impulsivity, unstable interpersonal relationships, and a distorted self-image.
Aleksandra Sokół   +9 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Inflation with TeV-scale gravity

open access: yes, 1998
Allowing for the possibility of large extra dimensions, the fundamental Planck scale $M$ could be anywhere in the range $\TeV\lsim M\lsim \mpl$, where $\mpl=2.4\times 10^{18}\GeV$ is the four-dimensional Planck scale.
Agrawal, Benakli, David H. Lyth, Linde
core   +3 more sources

Feeding the Mind: The Role of Fermented Foods and Probiotics in Anxiety Treatment

open access: yesQuality in Sport
Introduction:  Anxiety disorders represent the most common mental health disorders globally which makes their treatment a major clinical problem. Recent research has increasingly focused on the gut-brain axis, because scientists have discovered that gut
Marta Ignatiuk-Chilkiewicz   +9 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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