Results 131 to 140 of about 6,710,335 (243)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Madrid 15-M: lo poético político

open access: yes, 2014
Guillermo G. Peydró, en su escrito “Madrid, 15-M: lo poético político” nos interpela a través de una pregunta coyuntural: ¿en qué medida puede lo poético ser político, evitar la esterilización inevitable del negocio del arte contemporáneo, provocar algún cambio real?
openaire   +1 more source

El 15-M como discurso contrahegemónico

open access: yesEncrucijadas. Revista Crítica de Ciencias Sociales, 2011
El movimiento 15-M ha sido una irrupción inesperada en el panorama político español, que ha conseguido, desde su nacimiento, una enorme atención mediática y marcar en gran medida la agenda política española. En este artículo se defiende que una parte fundamental de su éxito político se debe a su capacidad de alterar las posiciones políticas dadas y ...
openaire   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

What is the best surgical approach for Pineal Region Tumors? A systematic literature review and anatomical comparative study. [PDF]

open access: yesChilds Nerv Syst
Palombi D   +14 more
europepmc   +1 more source

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