Results 131 to 140 of about 7,153,567 (281)

Physical Exercise as a Therapeutic Strategy for ADHD in Children and Adolescents

open access: yesQuality in Sport
Background: ADHD (Attention Deficit Hyperactivity Disorder) is one of the most commonly diagnosed neurobiological disorders in children and adolescents.
Klaudia Mościszko   +10 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Desbordamientos culturales en torno al 15-M The 15-M movement in its cultural context

open access: yesRevista Teknokultura, 2013
Este artículo es una exploración del contexto cultural amplio del movimiento 15-M en el estado español. Comienza por proponer que el 15-M es un síntoma más de un generalizado desgaste de la hegemónica “Cultura de la transición”, que estableció una serie de acuerdos tácitos en torno a la necesidad de una sociedad vertical y de expertos basada en el ...
openaire   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

15-M. La reaparición de las luciérnagas

open access: yesNómadas. Revista Crítica de Ciencias Sociales y Jurídicas, 2012
La extraordinaria sorpresa provocada por el surgimiento del llamado movimiento 15-M tiende a dejar en segundo plano el agudo deterioro de las condiciones de vida de la poblacion espanola que lo ha generado. Asimismo, la enorme decepcion que el movimiento refleja hacia la llamada clase politica es una consecuencia del peculiar desarrollo historico ...
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

CO deficiency in galaxies of the Fornax cluster? [PDF]

open access: yes
There is ample observational evidence that cluster galaxies are different from those in the field. Interaction with the hot intracluster medium affects the morphology of the galaxies, their gaseous content and possibly their star-formation activity ...
Casoli, Fabienne   +2 more
core   +1 more source

15-M, la gueule de bois

open access: yes, 2021
Le mouvement des Indignés, le 15-M, fut un mouvement d’une ampleur inédite, qui bouleversa des pans de la société espagnole. Il constitua, en Espagne et au-delà, un espoir de renouveau politique et social. C’était il y a dix ans déjà… Quelles traces en reste-t-il ? Le dossier de ce numéro tente de répondre à cette question.
openaire   +1 more source

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