Results 81 to 90 of about 170,483 (257)

Dynamically Modified Flexible Zn Powder Anodes with Stable Performance at High Rate and High Zn Utilization

Advanced Science, EarlyView.
A dynamically shape‐variant liquid metal‐based network is integrated into Zn powder electrode, where intrinsic fluidity and structural adaptability of the liquid metal‐based network enable effective mitigation of dendritic growth, alleviation of stress accumulation, and prevention of Zn loss during Zn plating‐stripping processes.
Yuxuan Wang, Chenhao Li, Wenbo Zhao, Yong Gao, Yiwei Liu, Yuhao Li, Yu Zhang, Yuhan Yao, Abdelnaby M. Elshahawy, Cao Guan   +9 more
wiley   +1 more source

Assessing the Status of Sustainable Development Goals in Global Mining Area

Land
Mining is an important industry for the achievement of sustainable development goals (SDGs), but it results in a significant amount of degraded land worldwide, thereby affecting local social and ecological sustainability. Little is known about the extent
Shurui Zhang, Yan Sun, Yan Zhang, Xinxin Chen, Zhanbin Luo, Fu Chen   +5 more
doaj   +1 more source

Epidermal METTL1‐Mediated m7G Modification Drives Psoriatic Inflammation by Stabilizing Bdkrb1 and Orchestrating Neutrophil Recruitment

Advanced Science, EarlyView.
This study unveils an unrecognized pro‐inflammatory epitranscriptomic checkpoint in psoriasis. By installing m7G modifications on the 5′ UTR of Bdkrb1 mRNA, METTL1 enhances receptor stability to orchestrate keratinocyte‐driven neutrophil recruitment via p38 MAPK signaling.
Chang Zhang, Jiayi Lu, Sihao Yan, Yirui Wang, Zhuo Li, Weiwei Chen, Yang Han, Ziyan Zhang, Yafen Yu, Qi Zhen, Liangdan Sun   +10 more
wiley   +1 more source

Adjunctive electrophysical therapies used in addition to land-based exercise therapy for osteoarthritis of the hip or knee: A systematic review and meta-analysis

Osteoarthritis and Cartilage Open
Objectives: To review evidence for effectiveness of electrophysical therapies (EPTs), used adjunctively with land-based exercise therapy, for hip or knee osteoarthritis (OA), compared with 1) placebo EPTs delivered with land-based exercise therapy or 2 ...
Helen P. French, Joice Cunningham, Rose Galvin, Sania Almousa   +3 more
doaj   +1 more source

Tumor‐Specific Delivery of CD28 siRNA via Lyso‐PC C‐16 Modified Lipid Nanoparticles Overcomes Anti‐PD‐1 Resistance by Remodeling Tumor Microenvironment

Advanced Science, EarlyView.
This study develops 16:0 LPC‐modified lipid nanoparticles (LPC‐LNPs) with cancer cell specificity by exploiting altered tumor lipid metabolism. LPC‐LNPs encapsulating Cd28 small interfering RNA (LPC‐LNP‐Cd28) knock down cancer cell CD28 without affecting T cells, inflame the tumor microenvironment, and overcome anti‐PD‐1 resistance.
Yangyang Chai, Keyu Wang, Jiali Fang, Shaorui Jia, Yansong Shi, Wanfeng Gao, Xinpeng Liu, Jiaqiang Li, Zenghui Cui, Yazhi Qian, Xiaosu Chen, Dan Ding, Xuetao Cao   +12 more
wiley   +1 more source

Large Language Model‐Informed Dual‐Track AI Framework for the Synergistic Design of Crack‐Free and High‐Strength Superalloys

Advanced Science, EarlyView.
This paper illustrates a knowledge‐augmented dual‐track AI framework for advanced superalloy design. First, Large Language Models translate metallurgical heuristics into explicit rules to rapidly prune a vast compositional search space. Subsequently, LLM‐distilled priors safely guide a reinforcement learning agent during autonomous process optimization,
Jian Yao, Junkang Wu, Jie Su, Fuzhu Wang, Zi Wang, Li Wang, Liming Tan, Lan Huang, Feng Liu, Yong Liu   +9 more
wiley   +1 more source

A Ceramic Network for Hybrid Solid Electrolyte Lithium Metal Batteries

Advanced Science, EarlyView.
An in‐plane aligned Ta‐LLZO ceramic network exhibits superior performance compared to conventional fillers, including single ceramic fibers and particles. The tortuosity within the polymeric phase of hybrid solid electrolytes is identified as a key parameter governing lithium‐ion transport pathways and dendrite suppression.
Luca Weckelmann, Jeong Seop Yoon, Jehad Ahmed, Krzysztof Dzieciol, Anna Windmüller, Luc Raijmakers, Sanja Tepavcevic, Hans Kungl, Venkat Srinivasan, Chih‐Long Tsai, Rüdiger‐A. Eichel   +10 more
wiley   +1 more source

Impacts of commodity prices and governance on the expansion of tropical agricultural frontiers

Scientific Reports
Deforestation in the tropics remains a significant global challenge linked to carbon emissions and biodiversity loss. Agriculture, forestry, wildfires, and urbanization have been repeatedly identified as main drivers of tropical deforestation ...
Javier Miranda, Wolfgang Britz, Jan Börner   +2 more
doaj   +1 more source

T2T Genome Assembly and Multi‐Omics Data Reveal Terrestrial Adaptation and Mucus Biosynthesis in Tropical Leatherleaf Slug (Laevicaulis alte)

Advanced Science, EarlyView.
A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang, Shaofang He, Zhongkai Wang, Aobo Pang, Xiaoli Sun, Rongchen Liu, Fang Wang, Sisi Chen, Zhijuan Bian, Dongcheng Wei, Liuhan Wu, Siyao Zhao, Qiuting Ji, Yiqi Sun, Niying Sun, Yushinta Fujaya, Boping Tang, Kianann Tan, Daizhen Zhang, Lianfu Chen   +19 more
wiley   +1 more source

Tandem Duplication‐Driven Neofunctionalization of UDP‐Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae

Advanced Science, EarlyView.
We present a chromosome‐level genome assembly of Siraitia grosvenorii and, through comparative genomics, uncover a conserved UGT73 tandem array driving triterpenoid saponin diversification in Cucurbitaceae. Crystalized SgUGT73AM30 further reveals the regioselectivity mechanism underlying its catalytic activity.
Guangyi Wang, Mengmeng Li, Xuehui Dai, Yanchen Zhang, Yuhan Wu, Zhaotao Yan, Chenfei Tian, Hongkai Fan, Haili Liu, Xiaowei Zhang, Yiming Yang, Jiayu Lu, Yuwei Sun, Yong Wang   +13 more
wiley   +1 more source