Results 121 to 130 of about 12,503,962 (333)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Nature at 150 [PDF]

Nature, 2019
openaire   +2 more sources

Referee comments on “Climatology of intermediate descending layers (150 km) over the equatorial and low latitude regions of Brazil during the deep solar minimum of 2009” by Ângela M. Santos et al.

, 2019
ngela Santos
openalex   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Gabinete Português de Leitura do Rio de Janeiro Resumo Cronoiconográfico

Convergência Lusíada, 1987
Do alto de seus 150 anos de existência, o Gabinete Português de Leitura do Rio de Janeiro ostenta títulos indisputáveis que lhe foram conferidos pela tradição, entre eles, Instituição-Mãe e Alma Máter das Associações Portuguesas do Brasil, Catedral da ...
Carlos Francisco Moura
doaj  

Assessment of SARS-CoV-2 Infection, Vaccination, and Immunity Status Among a Population of Dentists/Academic Professors in a Clinical Setting: One-Year Findings

COVID
Background: This study aimed to assess the prevalence of SARS-CoV-2 infection, vaccination, and immune status among a population, both Dentists and University Professors, within a clinical setting at one and at 12 months after COVID-19 vaccination ...
Patricia Manarte-Monteiro, Gabriella Marques, Dina Alves, Mary Duro, Joana Domingues, Sandra Gavinha, Lígia Pereira da Silva, Liliana Teixeira   +7 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

A Data-Driven Framework to Identify Tree Planting Potential in Urban Areas: A Case Study from Dortmund, Germany

Urban Science
Urban areas increasingly face heat-related climate risks, necessitating targeted, nature-based interventions such as tree planting to improve resilience, livability, and public health.
Vanessa Reinhart, Luise Wolf, Panagiotis Sismanidis, Benjamin Bechtel   +3 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Completely defined cell culture medium for advanced alveolar models

Current Directions in Biomedical Engineering
In vitro alveolar models are an important tool study respiratory physiology, investigate lung diseases, develop and test new therapies, and simulate inhalation exposure to environmental pollutants or therapeutic agents.
Nellinger Svenja, Heine Simon, Steeb Lothar, Kluger Petra J.   +3 more
doaj   +1 more source