Results 141 to 150 of about 36,481,988 (264)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

150 nezaboravljenih

open access: yesStudia Lexicographica, 2021
Kristian Lewis
doaj  

The Variability in the Pharmacokinetics of Follitropin Alfa: A Systematic Review. [PDF]

open access: yesClin Pharmacokinet
Kirubakaran R   +4 more
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

150 new students receive UMPSA Excellence Incentive [PDF]

open access: yes
GAMBANG, 29 September 2024 – A total of 150 outstanding students, who have completed their diplomas, matriculation, polytechnic, Vocational College, or the Malaysian Higher School Certificate (STPM), and were selected to pursue their studies at ...
Siti Nur Azwin, Zulkapri
core  

The zebrafish model tackles anti-P2Y12 variability in humans: a translational approach. [PDF]

open access: yesBlood Adv
Ciepla P   +7 more
europepmc   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

The Safety, Pharmacokinetics, and Antiviral Activity of ABI-4334, A Novel Next-Generation Hepatitis B Capsid Assembly Modulator. [PDF]

open access: yesJ Viral Hepat
Gane EJ   +11 more
europepmc   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

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