Results 191 to 200 of about 149,407 (284)

Residual Chemical Shift Anisotropies in the Structure Determination of Small Molecules

Magnetic Resonance in Chemistry, Volume 64, Issue 3, Page 286-311, March 2026.
Plasma neutrophil elastase(ELANE) was markedly elevated in patients with alcohol use disorder, indicating a dysregulated protease‐antiprotease inflammatory balance characterised by decreased SERPINA3. ELANE showed excellent diagnostic specificity(AUC = 0.8683), supporting its potential utility as a neuroinflammatory biomarker for AUD.
Nilamoni Nath, Juan Carlos Fuentes Monteverde, Swaraj Pathak, Christian Griesinger   +3 more
wiley   +1 more source

A high-resolution analysis of arrestin2 interactions responsible for CCR5 endocytosis. [PDF]

Elife
Petrovic I, Desai S, Isaikina P, Abiko LA, Spang A, Grzesiek S.   +5 more
europepmc   +1 more source

Multiplexed Analysis of Multicomponent Biomolecular Condensates without Any Tag. [PDF]

J Am Chem Soc
Pálfy G, Schmoll J, Pérez ME, Damberger FF, Han Y, Emmanouilidis L, Allain FH, Novakovic M.   +7 more
europepmc   +1 more source

Pharmacokinetic modeling strategies for dynamic hyperpolarized urea imaging

Magnetic Resonance in Medicine, Volume 95, Issue 3, Page 1671-1683, March 2026.
Abstract Purpose To evaluate pharmacokinetic modeling methods for quantification of tissue perfusion/permeability with hyperpolarized 13C urea. Methods Three models for quantitative analysis of dynamic HP urea imaging data were proposed and evaluated in numerical simulations and a thyroid cancer mouse model.
Keith A. Michel, Collin J. Harlan, Christopher M. Walker, Matthew E. Merritt, Yunyun Chen, Stephen Y. Lai, James A. Bankson   +6 more
wiley   +1 more source

Arg-Tyr cation-π interactions drive phase separation and β-sheet assembly in native spider dragline silk. [PDF]

Proc Natl Acad Sci U S A
Johnson HR, Chalek K, Elathram N, Chau AT, Domingo AR, Aldana JE, Nguyen H, de Loera A, Duarte BA, Shapakidze L, Onofrei D, Debelouchina GT, Lorenz CD, Holland GP.   +13 more
europepmc   +1 more source

Turn‐Induction in Peptides Incorporating Novel Cyrene‐Derived α,α‐Disubstituted Amino Acid

Journal of Peptide Science, Volume 32, Issue 3, March 2026.
Novel chiral cyrene‐derived Cyr residues were incorporated into peptides. The α,α‐disubstituted amino acid residue was introduced using the Ugi reaction. X‐ray crystallographic analysis of R‐ and S‐Cyr residues indicated preference to adopt left‐ and right‐handed α‐helical conformations, respectively.
Kajumee Bora Bhowal, Raphael Hitti, William D. Lubell   +2 more
wiley   +1 more source

Recognition of two hydrophobic pockets in the KIX domain of CBP by FOXO4 transactivation domain. [PDF]

Commun Biol
Heo J, Ryu KS, Park CJ.
europepmc   +1 more source

Cyclophilin D reduces Ca2+ sequestration by complement 1q binding protein. [PDF]

Biochem J
Adegbite O, Adegbite Y, Pickering C, Criddle DN, Lian LY.   +4 more
europepmc   +1 more source

Enhancement of Nitrogenase Activity in Recombinant Escherichia coli by Replacing Upstream Region of nif Operon from Paenibacillus Species

ChemBioChem, Volume 27, Issue 3, 12 February 2026.
Biological N2 fixation by nitrogenase offers a sustainable alternative to the Haber–Bosch process. Heterologous nitrogenase production in Escherichia coli is a promising strategy. We engineered E. coli with nitrogen fixation (nif) operons from diazotrophic Paenibacillus species.
Yuki Honda, Kotone Takeuchi, Sawako Hayakawa, Daisuke Koma, Hiroshi Fujii   +4 more
wiley   +1 more source

Side-chain-selective deuterium labeling by a simple bio-expression method enhances resolution and simplifies spectra in ¹H-detected protein solid-state NMR. [PDF]

J Biomol NMR
Shigemitsu Y, Miyazaki Y, Terami H, Ostapova D, Matsunaga T, Takahashi R, Inoue T, Yamazaki T, Ishii Y.   +8 more
europepmc   +1 more source