Results 211 to 220 of about 149,407 (284)

An Overview of Liquid Chromatography–Mass Spectrometry (LC–MS) Methods for the Quantification of Antibody‐Drug Conjugates

Biomedical Chromatography, Volume 40, Issue 2, February 2026.
ABSTRACT Antibody‐drug conjugates (ADCs) are innovative drugs composed of cytotoxic molecules (payload) linked to antibodies, that selectively target and kill cancer cells upon internalization. In vivo, ADCs exist as intact molecules, naked antibodies, or released, unconjugated (linker‐)payload.
Pauline L. M. Buitelaar, Hilde Rosing, Jos H. Beijnen, Neeltje Steeghs, Alwin D. R. Huitema   +4 more
wiley   +1 more source

Conservation agriculture raises crop nitrogen acquisition by amplifying plant-microbe synergy under climate warming. [PDF]

Nat Commun
Hao C, Dungait JAJ, Shang W, Hou R, Gong H, Yang Y, Lambers H, Yu P, Delgado-Baquerizo M, Xu X, Kumar A, Deng Y, Peng X, Cui Z, Kuzyakov Y, Zhou J, Zhang F, Tian J.   +17 more
europepmc   +1 more source

Mutations Alter Conformations and Dynamics of APP‐TMDs: An RDC Analysis

ChemistryEurope, Volume 4, Issue 2, February 2026.
How γ‐secretase selects its substrates has been an enigma because of the lack of a consensus sequence. Using residual dipolar couplings, we analyzed the conformations of one substrate and two mutants. Using snapshots of a molecular dynamics trajectory, we analyzed how well structures matched the measured RDC values.
Franziska Krause, Celine Moser, David Elsing, Mara Silber, Fabian Hoffmann, Yannik Woordes, Burkhard Luy, Claudia Muhle‐Goll   +7 more
wiley   +1 more source

Shifting the PPARγ conformational ensemble toward a transcriptionally repressive state improves covalent inhibitor efficacy. [PDF]

Elife
Arifova L, MacTavish BS, Laughlin Z, Karadi Girdhar MN, Shang J, Li MH, Yu X, Zhu D, Kamenecka TM, Kojetin DJ.   +9 more
europepmc   +1 more source

Nitrogen‐Doped Borane Cluster Network for High‐Performance Supercapacitors Under Universal pH Conditions

ChemSusChem, Volume 19, Issue 3, February 2026.
Nitrogen‐doped borane cluster network was prepared as a porous electrode material, featuring 1–2 nm micropores and specific surface area up to 626 m2 g−1. It delivers outstanding supercapacitor performance, reaching 607 F g−1 in a three‐electrode configuration and 354 F g−1 in an asymmetric supercapacitor device.
Abhishek Udnoor, Samikannu Prabu, Madhan Vinu, Matouš Kloda, Andrii Mahun, Libor Kobera, Michael G. S. Londesborough, Kung‐Yuh Chiang, Jan Demel   +8 more
wiley   +1 more source

Chemically induced deceleration of nuclear spin relaxation (CIDER) preserves hyperpolarization. [PDF]

Sci Adv
Peters JP, Assaf C, Brahms A, Them K, Gerdsen M, Herges R, Hövener JB, Pravdivtsev AN.   +7 more
europepmc   +1 more source

Brown Bear Consumption of Pacific Salmon Varies Greatly Among Individuals but Increases With the Bear's Age and Salmon Availability

Ecology and Evolution, Volume 16, Issue 2, February 2026.
Hair was sampled in a noninvasive manner from free‐living brown bears in Alaska and processed for genetic identification and stable isotopes. These data revealed great individual variation in bear reliance on salmon, despite being sampled along streams full of salmon.
Thomas P. Quinn, Jennifer H. Stern, N. Grace Henry, Annika K. McFeely, HyeJoo Ro, Blaise Stricker, Liz Voytas, Lisette P. Waits, Jennifer R. Adams, Aaron J. Wirsing   +9 more
wiley   +1 more source

A Computational Study of the NMR Chemical Shifts of Polynitropyrazoles. [PDF]

Magn Reson Chem
Alcorta A, Claramunt RM, Elguero J, Alkorta I.   +3 more
europepmc   +1 more source

Technologies and Strategies for Metabolic and Molecular Imaging With Hyperpolarized MRI

Journal of Magnetic Resonance Imaging, Volume 63, Issue 2, Page 310-327, February 2026.
ABSTRACT Conventional Magnetic Resonance Imaging (MRI) offers limited sensitivity for direct metabolic and molecular imaging using non‐proton nuclei due to low thermal nuclear spin polarization. Hyperpolarization (HP) technologies increase nuclear spin polarization by several orders of magnitude, overcoming this limitation to enable in vivo studies of ...
Alixander S. Khan, Christoffer Laustsen
wiley   +1 more source

Biochar one-off application for paddy soil ¹⁵N loss improvement: evidence from a two-year experiment. [PDF]

Front Plant Sci
Gao J, Sui Y, Zhang Z, Zhang K, Jiang H, Liu Y, Sun Z, Bing X, Zhao Y, Zhang W.   +9 more
europepmc   +1 more source