Results 221 to 230 of about 68,942 (307)

Covalent Targeting of Histidine Residues: A Ligand-First Approach. [PDF]

open access: yesJ Med Chem
Alboreggia G   +4 more
europepmc   +1 more source

Quantitative 2D Nuclear Magnetic Resonance of Complex Mixtures: From General Analytical Homo/Heteronuclear Methods to Intrinsically Quantitative HSQC Approaches

open access: yesChemistry–Methods, Volume 6, Issue 7, July 2026.
Quantitative 2D nuclear magnetic resonance methods provide accurate individual analyte concentrations in complex mixtures. This review provides a unified description and comparison of such methods, together with an overview of applications and practical implementation tips. Quantitative 2D nuclear magnetic resonance (NMR) spectroscopy has emerged as an
Jérémy Marchand   +3 more
wiley   +1 more source

Deciphering Catalytic Reaction Mechanisms for Low‐Temperature Ammonia Synthesis: Mechanism‐Guided Rational Design of Active Sites

open access: yesCarbon Neutralization, Volume 5, Issue 4, July 2026.
Low‐carbon ammonia synthesis urgently needs high‐efficiency low‐temperature catalysts. This review summarizes multiple reaction mechanisms, unveils structure–activity correlations, and offers design strategies for advanced ammonia synthesis catalysts.
Jinshu Tian   +9 more
wiley   +1 more source

Advances in Human Mass Balance Studies: An IQ Consortium Perspective on Current Practices and Emerging Trends

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 43-54, July 2026.
Human radiolabeled mass balance studies are crucial for comprehensively characterizing the absorption, distribution, metabolism, and excretion (ADME) of investigational drugs, providing essential data for drug development, regulatory evaluation, and product labeling.
Jason Boer   +24 more
wiley   +1 more source

Repurposing methyltransferase-cofactor interactions for engineered microbial production of isotopically labelled SAM and SAH. [PDF]

open access: yesMicrob Cell Fact
Bulgakova UV   +7 more
europepmc   +1 more source

Decoding the Structural Complexity of Fungal α‐ and β‐Glucan Matrix via Statistical Analysis of Solid‐State NMR Chemical Shifts

open access: yesIsrael Journal of Chemistry, Volume 66, Issue 4, July 2026.
Solid‐state NMR combined with principal component analysis enables quantitative classification of fungal α‐ and β‐glucan architectures in intact cell walls, revealing conserved triple‐helical β‐1,3‐glucan conformations across species and predominantly bundled‐sheet α‐1,3‐glucan assemblies with condition‐dependent polymorphism. Statistical clustering of
Ankur Ankur   +3 more
wiley   +1 more source

The Effect of Temperature on Trophic Discrimination of Stable Isotopes (13C and 15N) and Biokinetics in Common Carp (Cyprinus carpio, L. 1758)

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 6, Page 535-544, July 2026.
ABSTRACT Stable isotope analysis (SIA) provides essential information toward a better understanding of trophic ecology. However, the interpretation of SIA results relies on assumptions about the trophic discrimination factor (TDF), which aims to improve the accuracy but may lead to bias.
I. Kuklina   +6 more
wiley   +1 more source

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