Results 181 to 190 of about 418,926 (311)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Seasonal Baseline Evaluation of Physicochemical Parameters and Culturable Bacterial Characteristics in Northwestern Himalayan Ramsar Sites. [PDF]

Environ Microbiol Rep
Butt S, Kumari C, Shukla RK, Puri S, Pandey S, Kalsido AW.   +5 more
europepmc   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Clinical utility of 16S ribosomal ribonucleic acid gene polymerase chain reaction versus tissue culture in shoulder periprosthetic joint infections. [PDF]

JSES Int
Nguyen CN, Drake JH, Mounajjed MM, Cotter EJ, Grogan BF.   +4 more
europepmc   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Testing for Bacteria and Fungi in Cells and Ancillary Reagents-Probe-Based Quantitative PCR Assays. [PDF]

Cell Prolif
Cao J, Xu R, Fu B, Hao J, Wang L, Ma A, Wei Q, Zhao H, Rao C, Li Q, Na T, Hu S, Zhou L, Zhang W, Chen Q, Sun S, Liu Z, Niu S, Zhang T, Zhang Y, Gan Y, Wang S, Stacey GN, Wei J, Zhao T, Zhang YA.   +25 more
europepmc   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Genetic Variation and Demographic History of Green Weevil <i>Hypomeces pulviger</i> (Herbst, 1795) (Coleoptera: Curculionidae) in Thailand Examined by Mitochondrial DNA Sequences. [PDF]

Biology (Basel)
Pradit N, Pilap W, Jaroenchaiwattanachote C, Saijuntha J, Tawong W, Kongbuntad W, Laotongsan P, Wongpakam K, Inkhavilay K, Thanee I, Saijuntha W, Tantrawatpan C.   +11 more
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Doxycycline Resistance and 16S rRNA Mutations in Treponema pallidum (Response). [PDF]

Emerg Infect Dis
Long GS, Duvvuri VR.
europepmc   +1 more source