Results 241 to 250 of about 736,237 (386)

EzTaxon: a web-based tool for the identification of prokaryotes based on 16S ribosomal RNA gene sequences.

International Journal of Systematic and Evolutionary Microbiology, 2007
J. Chun, Jae-Hak Lee, Yoonyoung Jung, Myungjin Kim, Seil Kim, Byung Kwon Kim, Y. Lim   +6 more
semanticscholar   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Toxicity assessment of doxycycline-aided artificial intelligence-assisted drug design targeting candidate 16S rRNA methyltransferase gene. [PDF]

BMC Pharmacol Toxicol
Mubeen H, Rafiq N, Khan M, Jabeen S, Shoaib MW.   +4 more
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

<i>Kerstersia gyiorum-</i>Caused Chronic Osteomyelitis in a Male Patient with Cerebral Infarction: A Case Report and Literature Review. [PDF]

Infect Drug Resist
Zhang T, Zhu B, Huang C.
europepmc   +1 more source

Term 16

Medical Mycology Journal, 2017
openaire   +3 more sources

IncFII _k plasmid harbouring an amplification of 16S rRNA methyltransferase-encoding gene rmtH associated with mobile element IS CR2 [PDF]

, 2016
Racha Beyrouthy, Frédéric Robin, Monzer Hamzé, Richard Bonnet   +3 more
openalex   +1 more source

Isolation and direct complete nucleotide determination of entire genes. Characterization of a gene coding for 16S ribosomal RNA.

Nucleic Acids Research, 1989
U. Edwards, Till Rogall, H. Blöcker, Monica Emde, E. Böttger   +4 more
semanticscholar   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Gut microbiota and intestinal polyps: a systematic review and meta-analysis based on 16S rRNA gene sequencing. [PDF]

Gut Pathog
Wu Q, Lu S, Wang L, Liao X, Wei D.
europepmc   +1 more source