Results 241 to 250 of about 712,979 (385)

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Integrative microbiome- and metatranscriptome-based analyses reveal diagnostic biomarkers for peri-implantitis. [PDF]

NPJ Biofilms Microbiomes
Joshi AA, Szafrański SP, Steglich M, Yang I, Qu T, Schaefer-Dreyer P, Xiao X, Behrens W, Grischke J, Häussler S, Stiesch M.   +10 more
europepmc   +1 more source

The Gillick judgment. Contraceptives and the under 16s: House of Lords ruling. [PDF]

, 1985
C. Dyer
openalex   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Patients in hospital with confirmed bacterial airway infection are significantly more likely to have a respiratory virus co-infection. [PDF]

J Med Microbiol
Hamza YP, Kacem MABH, Al Molawi NH, Yassine HM, AlKhatib HAM, Benslimane F, Al-Remaihi HIKB, Awni El Kahlout R, Ahmed El Kahlout BI, Al Khalili H, Al Khalili MA, Doiphode SH, Elmagboul EBI, Akhter J, Al Kuwari EAE, Coyle PV.   +15 more
europepmc   +1 more source

Nucleotide sequence of 16S rRNA and phylogenetic position of the green sulfur bacterium Clathrochloris sulfurica [PDF]

, 1989
Dagmar Witt, Talya Bergstein-Ben Dan, Erko Stackebrandt   +2 more
openalex   +1 more source

Comparison of five genotypic techniques for identification of optochin-resistant pneumococcus-like isolates [PDF]

, 2003
Claeys, Geert, De Baere, Thierry, De Ganck, Catharine Clara, KAIJALAINEN, T, Van Simaey, Leen, Vaneechoutte, Mario, Verhelst, Rita, Verschraegen, Gerda   +7 more
core  

Rapid determination of 16S ribosomal RNA sequences for phylogenetic analyses.

Proceedings of the National Academy of Sciences of the United States of America, 1985
D. Lane, B. Pace, G. Olsen, D. Stahl, M. Sogin, N. Pace   +5 more
semanticscholar   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Rapid, Amplification-free, RNA-based Uropathogen Detection With LbuCas13a. [PDF]

Open Forum Infect Dis
Ata H, Hull ME, Geisler WM, Leal SM, Chilkoti A.   +4 more
europepmc   +1 more source