Results 241 to 250 of about 267,584 (295)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

A QIIME2-based workflow for multi-amplicon 16S rRNA profiling. [PDF]

Microbiol Resour Announc
Licata AG, Zoppi M, Dossena C, Rossignoli F, Rizzo D, Bergamaschi L, Nigro O, Chiaravalli S, Massimino M, De Cecco L.   +9 more
europepmc   +1 more source

Correction: Neonatal microbiota colonization primes maturation of goblet cell-mediated protection in the pre-weaning colon. [PDF]

J Exp Med
Johansson Å, Subramani MV, Yilmaz B, Nyström EEL, Layunta E, Arike L, Sommer F, Rosenstiel P, Vereecke L, Mannerås-Holm L, Wullaert A, Pelaseyed T, Johansson MEV, Birchenough GMH.   +13 more
europepmc   +1 more source

Exploring <i>Bacteroidota</i> strains from human stool and animal feces: phenotyping and functional diversity. [PDF]

Microlife
Ladewig L, Kinfu BM, Fokt H, Bethge H, Tufail MA, Baines JF, Schmitz RA.   +6 more
europepmc   +1 more source

Creating unity: linking 16S rRNA gene sequence information to the core taxonomy of genomes. [PDF]

Environ Microbiome
Vinje H, Rudi K, Snipen L.
europepmc   +1 more source

MMonitor for real-time monitoring of microbial communities using long reads. [PDF]

Cell Rep Methods
Lucas TN, Biehain U, Gautam A, Gemeinhardt K, Lass T, Konzalla S, Ley RE, Angenent LT, Huson DH.   +8 more
europepmc   +1 more source