Results 131 to 140 of about 396,782 (350)
Advanced Science, EarlyView.This study presents an engineered human interferon‐lambda (hIFN‐λ) as an intranasal prophylactic against respiratory viruses. By combining AI‐guided backbone redesign and glycoengineering, the authors developed a thermostable, protease‐resistant, and scalable variant with improved mucosal penetration.
Jeongwon Yun +12 more
wiley +1 more source
Use of RNA secondary structure for evolutionary relationships : investigating RNase P and RNase MRP : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Genetics at Massey University, New Zealand [PDF]
, 1998 Bioinformatics is applied here to examine whether RNA secondary structure data can reflect distant evolutionary relationships. This is important when there is little confidence in sequence data such as when looking at the evolution of RNase MRP (MRP ...
Collins, Lesley Joan
core
Advanced Science, EarlyView.This study establishes crucial genomic resources for adzuki bean, including a reference genome, variation map, and the AdzukiBeanAtlas toolkit. We identify key candidate genes (ANKRD50, NAC73, ANR1, NPF5.4) for important agronomic traits through Genome‐Wide Association Studies (GWAS).
Liangliang Hu +26 more
wiley +1 more source
浙江大学学报. 农业与生命科学版, 2015 Thermophilic bacterium, strain CHBT-1721 is the first thermophilic microorganism isolated from the hot spring of Bantang in Chaohu of Anhui Province and the phylogenetic relationship of this strain with other thermophile bacteria isolated from hot ...
Fang Shu, Dai Chong, Yan Juan
doaj +1 more source
Draft Genome Sequence ofStreptomycessp. Strain AM-2504, Identified by 16S rRNA Comparative Analysis as a Streptomyces kasugaensis Strain [PDF]
, 2019 Valerio Napolioni +7 more
openalex +1 more source
Advanced Science, EarlyView.Neural stem cell transplantation shows promise for spinal cord repair, but poor graft survival limits therapeutic efficacy. This study demonstrates that increasing hydrogel stiffness from 10% to 16% concentration significantly enhances transplanted neural stem cell survival through Piezo1‐mediated mechanotransduction, revealing mechanical properties as
Hee Hwan Park +19 more
wiley +1 more source
Advanced Science, EarlyView.The chimeric RNA ERCC1‐iASPP possesses dual coding and non‐coding functions, synergistically accelerating the process of cellular malignant transformation. Abstract Genetic variation at 19q13.3 critically modulates chemical carcinogen‐induced lung carcinogenesis, particularly in mediating the activity of benzo[a]pyrene (B[a]P), a major polycyclic ...
Mingming Shan +9 more
wiley +1 more source
Polymerase Chain Reaction Using 16S rRNA Gene Sequences Distinguishes the Two Biovars of Ureaplasma urealyticum [PDF]
, 1993 openalex +1 more source
Advanced Science, EarlyView.A novel melanin‐based therapeutic composed of ultrasmall polydopamine nanodots is employed as an efficient oral formulation for the targeted treatment of inflammatory bowel disease. The potential therapeutic mechanism of polydopamine nanodots mainly involves the elimination of excessive oxidative stress, the reduction of ROS‐mediated proinflammatory ...
Zhen Ding +11 more
wiley +1 more source