17-Hydroxyprogesterone in children, adolescents and adults
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 201417-Hydroxyprogesterone (17-OHP) is an intermediate steroid in the adrenal biosynthetic pathway from cholesterol to cortisol and is the substrate for steroid 21-hydroxylase. An inherited deficiency of 21-hydroxylase leads to greatly increased serum concentrations of 17-OHP, while the absence of cortisol synthesis causes an increase in ...
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Development of a Direct Fluoroimmunoassay for Serum Levels of 17-Hydroxyprogesterone
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1988A direct, rapid and highly specific fluoroimmunoassay for determining serum levels of 17-hydroxyprogesterone has been developed. It is based on the use of a sheep antiserum covalently coupled to magnetisable particles and fluorescein-labelled steroid.
B A, el-Gamal +3 more
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17-Hydroxyprogesterone Responses to Adrenocorticotropin in Children with Premature Adrenarche*
The Journal of Clinical Endocrinology & Metabolism, 1985The adrenal secretory response to an iv bolus dose of ACTH was measured in 10 girls (4-8 yr of age), 5 boys (4-9 yr) with premature adrenarche (PA), and 20 normal children. The evening before the ACTH test, each subject took dexamethasone (1 mg at bedtime) to suppress the early morning surge of ACTH.
A B, Granoff +2 more
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Vanishing 17-Hydroxyprogesterone Concentrations in 21-Hydroxylase Deficiency
Hormone Research in Paediatrics, 2018We present a boy with a genetically proven congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency. While massively elevated 17-hydroxyprogesterone (17-OHP) concentrations after birth led to the diagnosis, 17-OHP concentrations became immeasurable starting with the second year of life even though the dose of hydrocortisone was ...
Thomas Reinehr +5 more
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Serum 17-Hydroxyprogesterone is a Potential Biomarker for Evaluating Intratesticular Testosterone
Journal of Urology, 2020Intratesticular testosterone is essential for spermatogenesis and can only be reliably measured with invasive testicular sampling. Previous studies have demonstrated good correlation between intratesticular testosterone and serum 17-hydroxyprogesterone (17-OHP) in men treated with human chorionic gonadotropin.
Thiago Fernandes Negris, Lima +4 more
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17‐Hydroxyprogesterone response to buserelin testing in the polycystic ovary syndrome
Clinical Endocrinology, 1993SummaryOBJECTIVE We determined the 17‐hydroxyprogesterone (17‐OH P) response to buserelin, a GnRH agonist, and its relation to ovarian volume in the patients with polycystic ovary syndrome (PCOS).DESIGN We compared 17‐OH P response to buserelin in a large group of patients with that In a control group of healthy women.
KELESTIMUR, F, ŞAHİN, Yılmaz
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17-Hydroxyprogesterone Caproate and the Prevention of Preeclampsia [14G]
Obstetrics & Gynecology, 2019INTRODUCTION: Preeclampsia is a hypertensive disease caused by a dysfunction of the maternal and placental vasculature. Prior studies have shown that progesterone decreases inflammatory markers, mean arterial pressure and promotes vasodilation.
Ryley Lawrence Greenbaum +3 more
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17‐Hydroxyprogesterone rhythms and growth velocity in congenital adrenal hyperplasia
Journal of Paediatrics and Child Health, 1993AbstractSix patients on steroid replacement therapy for congenital adrenal hyperplasia provided capillary blood samples collected at 0800, 1200, 1700, and 2200h, on to filter paper for 17‐hydroxyprogesterone analysis. There was a strong correlation between 17‐hydroxyprogesterone day profiles and height velocity over a 4 year period of study.
D R, Pincus, C J, Kelnar, A M, Wallace
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Plasma 17-hydroxyprogesterone determination with two commercial immunoassays
The Journal of Steroid Biochemistry and Molecular Biology, 1994Plasma 17-hydroxyprogesterone (17-OH-P) was determined by two commercially available immunoassay kits, a radioimmunoassay (RIA) (OHP-CT, CIS) and an enzyme-immunoassay (EIA) (Serozyme 17 alpha-OH-progesterone, Serono). The determination by RIA was performed according to two procedures, directly on plasma or on a crude plasma extract, whereas that by ...
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Progesterone, 17-hydroxyprogesterone, estradiol, and estriol in late pregnancy and labor
American Journal of Obstetrics and Gynecology, 1980Levels of progesterone, 17 alpha-hydroxyprogesterone, estradiol, and estriol were measured in serial plasma samples collected from 30 uncomplicated pregnancies during the last eight weeks of gestation. From another group of 27 uncomplicated pregnancies, blood samples were collected during the second stage of labor and the same steroids were measured ...
R S, Mathur +2 more
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