Results 41 to 50 of about 130,309 (214)
Evaluation of [18F]-FDG-Based Hybrid Imaging Combinations for Assessment of Bone Marrow Involvement in Lymphoma at Initial Staging. [PDF]
, 2016 The purpose of our study was to determine the value of different hybrid imaging combinations for the detection of focal and diffuse bone marrow infiltration in lymphoma.Georgios Karanikas, Georgios Karanikas (2742550), Ramona Woitek, Richard Nolz (576234), Ulrika Asenbaum (475895), Ulrika Asenbaum, Michael Weber (134225), Ingrid Simonitsch-Klupp (469605), Ingrid Simonitsch-Klupp, Markus Raderer, Anton Staudenherz (3207150), Daniela Senn (3207147), Daniela Senn, Michael Weber, Anton Staudenherz, Julia Furtner, Ramona Woitek (475889), Richard Nolz, Julia Furtner (475896), Marius E. Mayerhoefer (607018), Marius E Mayerhoefer, Markus Raderer (607022), Senn Daniela, Simonitsch-Klupp Ingrid, Asenbaum Ulrika, Weber Michael, Mayerhoefer Marius E., Woitek Ramona, Furtner Julia, Staudenherz Anton, Nolz Richard, Karanikas Georgios, Raderer Markus +32 morecore +3 more sourcesReal‐World Effectiveness and Safety of Secukinumab in Giant Cell Arteritis: An Italian Multicenter Cohort Study
Arthritis Care &Research, EarlyView.Objective
The objective of this study was to evaluate the real‐world effectiveness and safety of secukinumab in patients with giant cell arteritis (GCA). Methods
This multicenter retrospective study included patients with GCA who received secukinumab at 14 Italian centers with at least six months of follow‐up.Luca Iorio, Federica Davanzo, Caterina Ricordi, Milena Bond, Ruggiero Mascolo, Jacopo Mora, Alessandro Tomelleri, Angelo Fassio, Francesca Cuzzocrea, Sara Monti, Edoardo Conticini, Fabiola Atzeni, Paolo Delvino, Carlotta Nannini, Augusta Ortolan, Francesco Pollastri, Ester Vivaldelli, Chiara Marvisi, Paola Toniati, Antonio Brucato, Alessandra Milanesi, Francesca Regola, Enrico Tombetti, Lorenzo Dagna, Roberta Ramonda, Christian Dejaco, Luca Quartuccio, Carlo Salvarani, Roberto Padoan +28 morewiley +1 more sourceAdditional file 2 of Evaluating the impact of 18F-FDG-PET-CT on risk stratification and treatment adaptation for patients with muscle-invasive bladder cancer (EFFORT-MIBC): a phase II prospective trial
, 2021 Additional file 2. 18F-FDG-PET-CT procedure.Maarten Albersen (4566958), Charles Van Praet (9912813), Sofie Verbeke (4216813), Piet Dirix (3095901), Gert De Meerleer (837672), Flor Verghote (11578636), Charlien Berghen (7341533), Daan De Maeseneer (4216804), Karel Decaestecker (4216807), Sylvie Rottey (3513308), Kathia De Man (8488272), Geert Villeirs (11578639), Valérie Fonteyne (837666), Piet Ost (837668), Pieter De Visschere (4216819), Lindsay Poppe (6950339) +15 morecore +1 more sourceAn Adipocyte MKK3–p38β Axis Preserves Insulin Responsiveness in Mice and Is Reciprocally Altered in Human Obesity
Advanced Science, EarlyView.The adipocyte MKK3–p38β axis emerges as an adaptive stress‐response pathway during obesity. Human visceral adipose tissue analyses, adipocyte‐specific mouse models, and primary adipocytes show that the MKK3–p38β axis supports insulin responsiveness by restraining p70S6K‐dependent inhibitory IRS1 feedback and preserving AKT–GLUT4 signaling. This pathway Edgar Bernardo, Nuria Matesanz, Jorge‐Luis Torres, Alba C. Arcones, Juan Ignacio Jiménez‐Loygorri, Alfonso Mora, Leticia Herrera‐Melle, Luis Leiva‐Vega, Maria Elena Rodriguez, Lourdes Hernández‐Cosido, Marta Leon, Paula Yong González, Teresa Durán, Tamara Parracho, Francisca Mulero, Rubén Nogueiras, J. Simon C. Arthur, Angel R. Nebreda, Roger J. Davis, Miguel Marcos, Guadalupe Sabio +20 morewiley +1 more sourceThe Adipose‐Sympathetic Nerve Crosstalk: FSTL1 as an Adipocyte‐Derived Neurotrophic Factor for WAT Browning
Advanced Science, EarlyView.As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.Xiao‐Wei Jia, Jia‐Xin Liu, Rui‐Ping Wang, Xue‐Qin Wu, Yao Che, Mu‐Chen Wu, Hong‐Wei Shang, Xin Lu, Tao Lu, Lu‐Lu Wang, Chun‐Yan Jiang, Dong‐Liang Fang, Chun Yang, Yan Gao +13 morewiley +1 more sourceNon-invasive visualization of pH changes within the tumor-micro-environment by positron emission tomography
EJNMMI ResearchBackground Acidic pH values of the tumor microenvironment (TME) have crucial effects on metastatic behavior, host defense, immune regulation and cellular metabolism.Jürgen Brück, Dominik Schauenburg, Seah Ling Kuan, Simeon Göttert, Benedikt Klasen, Veronika Frommberger, Kazem Ebadi Jalal, Nabil Boui, Aaron Kwiatkowski, Lisa Schake, Tobias Bopp, Tozka Bohn, Tanja Weil, Mathias Schreckenberger, Matthias Miederer +14 moredoaj +1 more sourcePET/CT with 18F-choline or 18F-FDG in Hepatocellular Carcinoma Submitted to 90Y-TARE: A Real-World Study
, 2022 Our aim was to assess the role of positron emission computed tomography (PET/CT) with 18F-choline (18F-FCH) or 18F-fluorodeoxyglucose (18F-FDG) in hepatocellular carcinoma (HCC) submitted to 90Y-radioembolization (90Y-TARE).Luca Filippi, Adelchi Saltarelli, Schillaci, Orazio, Bagni, Oreste, Cesare Ambrogi, Ermanno Notarianni, Saltarelli, Adelchi, Ambrogi, Cesare, Oreste Bagni, Notarianni, Ermanno, Orazio Schillaci, Filippi, Luca, Ambrogi C, Notarianni E, Filippi L, Bagni O, Schillaci O., Saltarelli A +17 morecore +1 more sourceAARS1‐Mediated H3K27 Lactylation Rewires Glycolysis to Sustain Aggressive and Recurrent Bladder Cancer
Advanced Science, EarlyView.AARS1 drives PI3K–AKT–mTOR‐dependent glycolysis in bladder cancer, promoting lactate accumulation, increased lactylation, H3K27la enrichment at the HK2 promoter, and HK2 transcription. HK2 reinforces glycolysis, sustaining a metabolic–epigenetic program associated with tumor progression, recurrence, and metastasis.Qin Yuan, Tianbao Song, Yipeng He, Sihan Xia, Yaoqiu Huang, Wenlin He, Qin Yi, Zefeng Wang, Peihan Wang, Chenbo Huang, Linzhi Li, Zhen Yin, Fan Cheng, Weimin Yu +13 morewiley +1 more sourceDual Tracers of 16α-[18F]fluoro-17β-Estradiol and [18F]fluorodeoxyglucose for Prediction of Progression-Free Survival After Fulvestrant Therapy in Patients With HR+/HER2- Metastatic Breast Cancer
Frontiers in Oncology, 2020 ObjectiveThe purpose of this study was to employ dual tracers 16α-[18F]fluoro-17β-estradiol (18F-FES) and [18F]fluorodeoxyglucose (18F-FDG) as imaging biomarkers in predicting progression-free survival (PFS) in ER-positive metastatic breast cancer (MBC ...Cheng Liu, Cheng Liu, Cheng Liu, Cheng Liu, Cheng Liu, Xiaoping Xu, Xiaoping Xu, Xiaoping Xu, Xiaoping Xu, Xiaoping Xu, Huiyu Yuan, Huiyu Yuan, Huiyu Yuan, Huiyu Yuan, Huiyu Yuan, Yongping Zhang, Yongping Zhang, Yongping Zhang, Yongping Zhang, Yongping Zhang, Yingjian Zhang, Yingjian Zhang, Yingjian Zhang, Yingjian Zhang, Yingjian Zhang, Shaoli Song, Shaoli Song, Shaoli Song, Shaoli Song, Shaoli Song, Zhongyi Yang, Zhongyi Yang, Zhongyi Yang, Zhongyi Yang, Zhongyi Yang +34 moredoaj +1 more source