Results 171 to 180 of about 140,614 (262)

C–X–C Motif Chemokine Receptor 4 (CXCR4)‐Targeted Biologically Guided Proton Spatially Fractionated Radiotherapy for Bulky Limited‐Stage Small Cell Lung Cancer

Precision Radiation Oncology, EarlyView.
A newly proposed proton spatially fractionated radiotherapy guided by biological imaging Abstract Background and Purpose To evaluate the feasibility and dosimetric safety of integrating C–X–C motif chemokine receptor 4 (CXCR4)‐targeted tracer 18F‐AlF‐NOTA‐QHY‐04 positron emission tomography imaging with biologically guided proton spatially fractionated
Keru Pu, Tengxiang Li, Shengnan Xu, Xue Sha, Qingtao Qiu, Jinming Yu, Yong Yin, Jie Liu   +7 more
wiley   +1 more source

Feasibility of Urethra‐Sparing Ultra‐Hypofractionated Three‐Dose‐Level Radiotherapy for Prostate Cancer with a Dominant Intraprostatic Lesion Abutting the High‐Dose Avoidance Zone

Precision Radiation Oncology, EarlyView.
Ultra‐hypofractionated three‐dose‐level radiotherapy allows safe dose escalation to dominant intraprostatic lesions near the urethra while maintaining full coverage of pelvis and prostate and respecting urethral and organ‐at‐risk constraints. Abstract This planning study evaluated ultra‐hypofractionated three‐dose‐level radiotherapy for prostate cancer
Annalisa Muscato, Denis La Fauci, Anna Viola, Valentina Zagardo, Gianluca Ferini   +4 more
wiley   +1 more source

[¹⁸F]FET uptake in diffuse lower-grade IDH-mutant glioma correlates with glioma-related epilepsy. [PDF]

J Neurooncol
Özdemir Z, Roll W, Stummer W, Kovac S, Müther M.   +4 more
europepmc   +1 more source

Boron‐embedded multifunctional nanoplatform toward potential combined boron neutron capture therapy and immunomodulation in glioma

Smart Molecules, EarlyView.
A brain‐targeting multifunctional nanoplatform (DM&Ce6@COF‐Ang) was engineered by employing boron‐enriched APTES‐COF‐1 as both the therapeutic boron agent and the nanocarrier co‐delivery of DMXAA and Ce6. This nanoplatform achieved synergistic tumor‐specific boron delivery, real‐time pharmacokinetic monitoring, and immunomodulation.
Yiming Liu, Xuejian Wang, Bangjian Li, Kun Shao, Jianlong Su, Yang Wang, Lin Cheng, Zhihao Wu, JinRong Li, Guanyi Zhang, Xu Wang, Yuxuan Zhang, Yuanhao Liu, Guangzhe Li   +13 more
wiley   +1 more source

Effect of data-driven gating on the quantification of prostate cancer metastases in ⁶⁸Ga-PSMA- and ¹⁸F-DCFPyL-PSMA PET/CT. [PDF]

EJNMMI Rep
Farag A, Felder C, Hussey D, Mirshahvalad SA, Harsini S, Metser U, Veit-Haibach P.   +6 more
europepmc   +1 more source

Current Advances of Treatments, Therapeutic Targets, Biomarkers, Novel Drugs, and Machine Learning for Hypopharyngeal Squamous Cell Carcinoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Hypopharyngeal squamous cell carcinoma (HSCC) is an aggressive subtype of head and neck squamous cell carcinoma with insidious onset, early metastasis, and dismal prognosis. Conventional multimodal therapy achieves limited survival benefit, highlighting an urgent need for refined precision strategies.
Ce Li, Rui Guan, Rui‐Jie Jiao, Zhi‐Jie Bi, Yang Fu, Yin Wang, Chen‐Yang Xu, Ye Qian, Ran Wei, Sheng‐Da Cao, Wen‐Ming Li, Dong‐Min Wei, Da‐Peng Lei   +12 more
wiley   +1 more source

Platelet activation and thrombosis in microvascular obstruction. [PDF]

Eur Heart J Cardiovasc Imaging
Balmforth C, Giaj Levra A, Whittington B, Morgan A, Macaskill MG, Tzolos E, Jordan AJ, Ramtoola T, Clark T, Rooney M, Lucatelli C, van Beek EJR, Slomka PJ, Sellers SL, Koglin N, Stephens AW, Hardewig I, Newby DE, Williams MC, Dweck MR.   +19 more
europepmc   +1 more source

Bi[IrBi6I12], Ag3[IrBi6I12], and BixCu3–3x[IrBi6I12]: Rock‐Salt Superstructures Based on Heavy‐Atom Clusters

Zeitschrift für anorganische und allgemeine Chemie, EarlyView.
New iridium‐containing bismuth subiodides based on cuboctahedral [IrBi6I12]3− clusters adopt chain‐like or rock‐salt‐related structure variants depending on the counter‐cations. Ag3[IrBi6I12] combines silver mobility at room temperature with long‐range ordering at low temperature, while DFT calculations reveal semiconducting behavior.
Noah Elsner, Vitaliy Romaka, Thomas Doert, Michael Ruck   +3 more
wiley   +1 more source

Tau-PET correlates of mild behavioral impairment in preclinical and prodromal Alzheimer's disease: A head-to-head comparison of Flortaucipir and MK6240. [PDF]

Alzheimers Dement
Bizzi I, Macedo AC, Trudel L, Therriault J, Rahmouni N, Lussier FZ, Tissot C, Bezgin G, Aumont É, Chan T, Hosseini SA, Oliva-Lopez D, Gonçalves MP, Povala G, Ferreira PCL, Bellaver B, Amaral L, Ruppert E, Medeiros MS, Mroué R, Rocha A, Ng KP, Zimmer ER, Masdeu J, Pascual B, Lowe VJ, Oh H, Soleimani-Meigooni DN, Fortea J, Ismail Z, Baker S, Pascoal TA, Rosa-Neto P, HEAD Study.   +33 more
europepmc   +1 more source

Development of an automated system for synthesizing 18F-labeled compounds using [18F]fluoroethyl bromide as a synthetic precursor

An automated system was developed to synthesize 18F-labeled compounds using [18F]fluoroethyl bromide ([18F]FEtBr)as a synthetic precursor. The apparatus makes possible the following sequence of processes: (1)production of an aqueous solution of [18F ...
Furutsuka, Kenji, Suzuki, Kazutoshi, 鈴木 和年, Tsuchiyama, Akio, 原田平 輝志, Yoshida, Yuichirou, 440279, 440278, 440277, 440276, 440275, 440274, 440273, 440283, 440282, Zhang, Ming-Rong, 440281, 古塚 賢士, 張 明栄, 440280, 吉田 勇一郎, Haradahira, Terushi   +21 more
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