Results 21 to 30 of about 875,017 (312)

Footwear soles friction on steel and tile surfaces: Experiments and modeling

Friction
Understanding and modeling the friction between footwear soles and substrates is important to avoid slips. In this study, we measure the friction force for three different footwear soles sliding on steel and tile surfaces. We use a vulcanized rubber (RU),
Lasse Jakobsen, Avinash Tiwari, Ion Marius Sivebaek, Bo Persson   +3 more
doaj   +1 more source

The Fictitious Audience of 1 Peter

The Heythrop Journal, 2019
Recent scholarship has argued that Simon Peter is not the author of 1 Peter, whilst maintaining that the addressees in 1:1 are the real recipients of the letter. We contend that both the stated author and the stated audience are part of the author’s deception.
Robinson, Will, Llewelyn, Stephen R.
openaire   +3 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Determining the temperature of a millikelvin scanning tunnelling microscope junction

Communications Physics, 2023
Cooling the junction of a scanning tunneling microscope to millikelvin temperatures is fundamental for high-resolution scanning tunneling spectroscopy.
Taner Esat, Xiaosheng Yang, Farhad Mustafayev, Helmut Soltner, F. Stefan Tautz, Ruslan Temirov   +5 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

High dose-rate brachytherapy of localized prostate cancer converts tumors from cold to hot

Journal for ImmunoTherapy of Cancer, 2020
Background Prostate cancer (PCa) has a profoundly immunosuppressive microenvironment and is commonly immune excluded with few infiltrative lymphocytes and low levels of immune activation.
Shahneen Sandhu, Paul J Neeson, Simon P Keam, Heloise Halse, Thu Nguyen, Minyu Wang, Nicolas Van Kooten Losio, Catherine Mitchell, Franco Caramia, David J Byrne, Sue Haupt, Georgina Ryland, Phillip K Darcy, Piers Blombery, Ygal Haupt, Scott G Williams   +15 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Linked skyrmions in shifted magnetic bilayer

Communications Physics
Magnetic solitons have recently attracted significant attention due to their intricate physical properties and potential applications in information processing.
Sumit Ghosh, Hiroshi Katsumoto, Gustav Bihlmayer, Moritz Sallermann, Vladyslav M. Kuchkin, Filipp N. Rybakov, Olle Eriksson, Stefan Blügel, Nikolai S. Kiselev   +8 more
doaj   +1 more source

Die eskatologie van 1 Petrus: hoop en vindikasie vir tydelike en permanente uitlanders

In die Skriflig, 2010
The eschatology of 1 Peter: hope and vindication for visiting and resident strangers The addressees of 1 Peter were living in an unfriendly environ-ment.
Fika Janse van Rensburg
doaj   +1 more source