Results 21 to 30 of about 32,304,583 (219)

Interface-driven formation of a two-dimensional dodecagonal fullerene quasicrystal

Nature Communications, 2017
Quasicrystals promise exciting technological advances in optical devices, but their formation mechanism is yet not fully understood. Here, the authors describe a two-dimensional dodecagonal fullerene quasicrystal, forming on a Pt3Ti(111)-surface due to ...
M. Paßens, V. Caciuc, N. Atodiresei, M. Feuerbacher, M. Moors, R. E. Dunin-Borkowski, S. Blügel, R. Waser, S. Karthäuser   +8 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Determining the temperature of a millikelvin scanning tunnelling microscope junction

Communications Physics, 2023
Cooling the junction of a scanning tunneling microscope to millikelvin temperatures is fundamental for high-resolution scanning tunneling spectroscopy.
Taner Esat, Xiaosheng Yang, Farhad Mustafayev, Helmut Soltner, F. Stefan Tautz, Ruslan Temirov   +5 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Clinical, FDG-PET and molecular markers of immune checkpoint inhibitor response in patients with metastatic Merkel cell carcinoma

Journal for ImmunoTherapy of Cancer, 2020
Background Metastatic Merkel cell carcinoma (mMCC) is an aggressive neuroendocrine malignancy of the skin with a poor prognosis. Immune checkpoint inhibitors (ICIs) have shown substantial efficacy and favorable safety in clinical trials.Methods Medical ...
Anthony J Gill, Shahneen Sandhu, George Au-Yeung, Grant A McArthur, Alison M Weppler, Andrew Pattison, Prachi Bhave, Paolo De Ieso, Jeanette Raleigh, Athena Hatzimihalis, Shiva Balachander, Jason Callahan, Margaret Chua, Rodney J Hicks, Richard W Tothill   +14 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Linked skyrmions in shifted magnetic bilayer

Communications Physics
Magnetic solitons have recently attracted significant attention due to their intricate physical properties and potential applications in information processing.
Sumit Ghosh, Hiroshi Katsumoto, Gustav Bihlmayer, Moritz Sallermann, Vladyslav M. Kuchkin, Filipp N. Rybakov, Olle Eriksson, Stefan Blügel, Nikolai S. Kiselev   +8 more
doaj   +1 more source

High dose-rate brachytherapy of localized prostate cancer converts tumors from cold to hot

Journal for ImmunoTherapy of Cancer, 2020
Background Prostate cancer (PCa) has a profoundly immunosuppressive microenvironment and is commonly immune excluded with few infiltrative lymphocytes and low levels of immune activation.
Shahneen Sandhu, Paul J Neeson, Simon P Keam, Heloise Halse, Thu Nguyen, Minyu Wang, Nicolas Van Kooten Losio, Catherine Mitchell, Franco Caramia, David J Byrne, Sue Haupt, Georgina Ryland, Phillip K Darcy, Piers Blombery, Ygal Haupt, Scott G Williams   +15 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source