Results 41 to 50 of about 778,058 (302)
A simple and mild protocol towards the synthesis of new 1,2,3-triazole compounds derived from acridone has been developed via regiospecific 1,3-dipolar cycloaddition reaction between 10-(prop-2-yn-1-yl)acridone derivatives and aromatic azides using CuI ...
Mohammed Aarjane +3 more
doaj +1 more source
1H-NMR based lipid profiling of Gossypium hirsutum seed oil at different developmental stages
1H-NMR spectroscopy is emerging as powerful robust analytical technique in analyzing bio constituents present in plants. It offers non-invasive method for identification and quantification of several Phyto-constitutes in a single step without much pre ...
Nikita J. Kurkuri +3 more
doaj +1 more source
Metabolic profiling framework for discovery of candidate diagnostic markers of malaria [PDF]
Despite immense efforts to combat malaria in tropical and sub-tropical regions, the potency of this vector-borne disease and its status as a major driver of morbidity and mortality remain undisputed.
Utzinger, Juerg +8 more
core +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Structural Elucidation of Hybutimibe
The structure of hybutimibe was analyzed by ultraviolet absorption spectroscopy, infrared absorption spectroscopy, mass spectrometry, nuclear magnetic resonance (1H NMR, 13C NMR, DEPT, 1H-1H COSY, 1H-1H NOESY, 1H-13C HSQC and 1H-13C HMBC) spectroscopy ...
XU Xiaojie +6 more
doaj +1 more source
A Wide-Line Solid-State 1H NMR Study of Phase Structures of Semi-Crystalline Polymers
Wide-line solid-state proton nuclear magnetic resonance (1H NMR) spectrometry is a classical technique to study the phase structures of semi-crystalline polymers.
WU Jin-ze +3 more
doaj +1 more source
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Biological 1H NMR spectroscopy
Proton nuclear magnetic resonance spectroscopy (1H NMR) is a powerful analytical method used to identify and quantitate chemical compounds. In recent years, it has been used to study rates of metabolism in microbes, isolated perfused tissues, intact animals, and human beings.
openaire +2 more sources
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
1H-NMR metabolomics for wine screening and analysis
The number of metabolomic studies has grown steadily over the last twenty years. Among the fields of application, food sciences are broadly represented.
Inès Le Mao +2 more
doaj +1 more source

