Results 41 to 50 of about 120,417 (300)

The conceptual model of two-generational business model innovation in family firms: Case study of family firms in the publishing industry [PDF]

ارزش آفرینی در مدیریت کسب و کار
The purpose of the research is to explain the capabilities of two generations in business model innovation through value creation in family companies and to present a conceptual model.
Maryam Vajdi Vahid, Jahangir Yadollahi Farsi, Kamal Sakhdari, Mehran Rezvani   +3 more
doaj   +1 more source

Generation mean analysis of important yield traits in Bitter gourd (Momordica charantia)

Journal of Horticultural Sciences, 2021
Generation mean analysis study in bitter gourd was undertaken using six basic generations viz. P1, P2, F1, F2, B1 and B2 population derived from crossing gynoecious line (IIHRBTGy - 491) with two monoecious lines (IIHR Sel -19 -1 and IIHR Sel-78-4).
Swamini Bhoi, B Varalakshmi, E Srinivasa Rao, M Pitchaimuthu, K Hima Bindu   +4 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Efficacy and safety of first- versus second-generation Bruton tyrosine kinase inhibitors in chronic lymphocytic leukemia: a systematic review and meta-analysis

Frontiers in Pharmacology
We conducted this first systematic review and meta-analysis to assess the competitive advantage of 2nd-generation Bruton tyrosine kinase inhibitors (BTKi) compared to 1st-generation BTKi in chronic lymphocytic leukemia (CLL).
Liyuan Ke, Su Li, Danxue Huang, Yan Wang
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Occurrence, bionomics and harmfulness of Chrysomela populi L. (Coleoptera, Chrysomelidae)

Journal of Forest Science, 2006
In 2003 to 2005, Chrysomela populi L. gradated on yearly cut Populus nigra var. italica in street alleys in Brno and elsewhere. Imagoes occurred on trees from the end of April or from the beginning of May. In rearing, the chrysomelid consumed unwillingly
J. Urban
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

The effect of yeast generations on fermentation, maturation and volatile compounds of beer

Czech Journal of Food Sciences, 2020
The aim of the study was to determine the effect of yeast generations on fermentation and maturation processes, the content of volatile compounds of beer and viability and vitality of yeast biomass on an industrial scale.
Krzysztof Kucharczyk, Tadeusz Tuszyński, Krzysztof Żyła, Czesław Puchalski   +3 more
doaj   +1 more source

Abundance and Generation Determination of the Mango Shield Scale Milviscutulus mangiferae (Green) (Coccidae: Homoptera) an Invasive Coccid Infesting Mango Orchards at Qaliobiya Gevernorate [PDF]

Journal of Plant Protection and Pathology, 2018
The obtained results showed that the population fluctuation of Milviscutulus mangiferae (Green)was studied on mango trees for the two successive years (2016/2017) and (2017-2018) in Qalubyia Governorate, the activity of M. mangifrae took place from early
Maha Abd Elrazzik, Sahar Attia, Sahar Abd-Elaziz   +2 more
doaj   +1 more source

Dewarless Logging Tool - 1st Generation [PDF]

, 2000
This report focuses on Sandia National Laboratories' effort to create high-temperature logging tools for geothermal applications without the need for heat shielding. One of the mechanisms for failure in conventional downhole tools is temperature. They can only survive a limited number of hours in high temperature environments.
Henfling, Joseph A., Normann, Randy A.
openaire   +2 more sources