Results 51 to 60 of about 120,417 (300)
Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi +19 morewiley +1 more sourceA Long Baseline Neutrino Oscillation Experiment Using J-PARC Neutrino Beam and Hyper-Kamiokande [PDF]
, 2014 Document submitted to 18th J-PARC PAC meeting in May 2014. 50 pages, 41 figuresDocument submitted to 18th J-PARC PAC meeting in May 2014. 50 pages, 41 figuresDocument submitted to 18th J-PARC PAC meeting in May 2014.Detwiler, J, Kudenko, Y., Sobel, H. W., Nunokawa, H, Mariani, C., Minakata, H, Rubbia, A, Tomura, T, Aihara, H, Learned, JG, Redij, A., Tsukamoto, T, Perez, J, Ludovici, L, Thompson, LF, Sobczyk, J., Lagoda, J., Dewhurst, D, Beltrame, P., Berardi, V., Rosa, G De, Luise, S Di, Detwiler, J., Kim, JY, Nakayama, S, Kajita, T., Densham, C, Kropp, W. R., Radicioni, E., Wilking, MJ, Needham, M, Oyama, Y., Kormos, L. L., Perkin, J. D., Bolognesi, S., Shiozawa, M, Sakuda, M., Fujii, Y, Yanagisawa, C., Ereditato, A, Kishimoto, Y, Shimizu, I., Quinto, M, Labarga, L., Kudenko, Y, Taketa, A., Sanchez, M. C., Sanchez, MC, Wilkes, RJ, Yamamoto, K, Rountree, SD, Thorpe, M, Riccio, C., Touramanis, C., Bronner, C, Suzuki, AT, Ikeda, M., Hadley, DR, Kropp, WR, Minamino, A, Tzanov, M., Svoboda, R., Khotjantsev, A., Abe, K., Smy, MB, Rose, HJ, Palladino, V., Tanaka, H., Barr, G., Sekiguchi, T, Ariga, T, Malek, M, Scantamburlo, E., Mezzetto, M, Sinnis, G., Lagoda, J, Carminati, G, Sobel, HW, Tanaka, HA, Collazuol, G., Haga, Y, O'Sullivan, E., Shaikhiev, A, Palladino, V, Sinnis, G, Palomino, JL, Mariani, C, Xin, T, Longhin, A., McFarland, K. S., Nicholls, T., Short, S, Cremonesi, L, Fitton, M, Mazzucato, E, Barbi, M, Nakahata, M., Nowak, J., Smy, M. B., Huang, K, Nowak, J, Lodovico, F. Di, Miura, M., Kuze, M, Drapier, O., Himmel, A, Collazuol, G, Ludovici, L., Karadhzov, Y., Back, JJ, Boyd, SB, Hirota, S., Stewart, T., Jang, HI, Sacco, R, Inoue, K, Tomura, T., Pistillo, C, Barker, G. J., Ganezer, K, O'Sullivan, E, Cafagna, F. S., Oyama, Y, Huang, K., Hierholzer, M, Minamino, A., Perkin, JD, Kobayashi, T., Suda, Y., Martin, JF, Scantamburlo, E, Owen, RA, Labarga, L, Ichikawa, AK, Seiya, Y., Haesler, A, Bay, F, Scott, M, Mueller, T., Irvine, T., Emery, S., Blaszczyk, FDM, Jamieson, B, Lodovico, F Di, Berry, T, Hill, J, Zito, M., Kim, SB, Barr, G, Okumura, K, Jamieson, B., Ariga, A, Nakaya, T, Touramanis, C, Vasseur, G, Moriyama, S, Lawe, M., Konaka, A, Nunokawa, H., Shiozawa, M., Korzenev, A, Bhadra, S., Berkman, S, Bolognesi, S, Fujii, Y., Gonin, M., Scholberg, K., Ishino, H., Tacik, R., Yershov, N, Irvine, T, Seiya, Y, Stewart, T, Rondio, E, Catanesi, M. G., Carminati, G., Feusels, T., McGrew, C., Miura, M, Fukuda, D., Yershov, N., Beltrame, P, Suda, Y, Luise, SD, Ishitsuka, M, Anghel, I., Rott, C., Horiuchi, S, Tanaka, H. K. M., Playfer, S, Blondel, A., Hartz, M, Koga, M, Luise, S. Di, Haesler, A., Izmaylov, A, Lim, IT, Koshio, Y., Gonin, M, Tzanov, M, Drapier, O, Ariga, T., Learned, J. G., Galymov, V., Muheim, F., Okajima, Y., Finch, A., Ross-Lonergan, M, McFarland, KS, Moriyama, S., Mueller, T, Zito, M, Intonti, R. A., Laveder, M., Terri, R., Magaletti, L., O'Keeffe, H. M., Nishimura, Y., Kaboth, A., Cafagna, FS, Mezzetto, M., Itow, Y., Uchida, Y, Martins, PPJ, Terri, R, Imber, J., Feusels, T, Radicioni, E, Wascko, M. O., Anghel, I, Perez, J., Mahn, K, Quilain, B, Takeda, A., Ishida, T., Tanaka, HKM, Wark, D, Richard, E., Barbi, M., Wilking, M. J., Magaletti, L, Itow, Y, Vogelaar, RB, Nakamura, K., Tobayama, S, Yano, T, Kormos, LL, Densham, C., Andreopoulos, C., Wilkes, R. J., McCauley, N, Bronner, C., Shimizu, I, Bhadra, S, Nirkko, M., Jiang, M, Program Advisory Committee (PAC) for Nuclear and Particle Physics Experiments at the J-PARC 50 GeV Proton Synchrotron, Stone, JL, Paolone, V, Haga, Y., Paolone, V., Wendell, R., Insler, J, Vagins, MR, Ereditato, A., Mineev, O., Perevozchikov, O., Payne, D., Rayner, M., Asfandiyarov, R., Barker, GJ, Korzenev, A., Ravonel, M., Muheim, F, Kearns, E., Joo, KK, Davies, G, Sacco, R., Posiadala-Zezula, M, Takeda, A, Sekiguchi, T., Ravonel, M, Cartwright, SL, Mori, T, Group, Hyper-Kamiokande Working, Oser, S. M., Hirota, S, McGrew, C, Wascko, MO, Thorpe, M., Longhin, A, Tanaka, H, Sakuda, M, Lindner, T., Berardi, V, Quinto, M., Monroe, J, Katori, T., Jung, CK, Kameda, J, Rubbia, A., Uchida, Y., Malek, M., Mineev, O, Joo, K. K., Imber, J, Pac, MY, Taketa, A, Fukuda, D, Berkman, S., Rosa, GD, Tolich, N., Mine, S, Bravar, A., Poutissou, J-M, Dewhurst, D., Fitton, M., Hierholzer, M., Hartfiel, B., Tsukamoto, T., Hadley, D. R., Ratoff, P. N., Koshio, Y, Retiere, F, Kearns, E, Group, H-KW, Kajita, T, Khabibullin, M., Playfer, S., Ishida, T, Ichikawa, A. K., Karadhzov, Y, Posiadala-Zezula, M., Palomino, J. L., Kutter, T., Fukuda, Y, Payne, D, Rayner, M, Konaka, A., Lodovico, FD, Yamamoto, K., Finch, A, Galymov, V, Hayato, Y., Riccio, C, Monroe, J., Abe, K, Horiuchi, S., Tobayama, S., Vagins, M. R., Martins, P. P. J., Retiere, F., Rondio, E., Lim, I. T., Yen, S., McCauley, N., Yen, S, Minakata, H., Fukuda, Y., Svoboda, R, Izmaylov, A., Bergevin, M, Sobczyk, J, Noah, E., Nakamura, K, Takeuchi, Y, Poutissou, J. -M., Weber, A., Rountree, S. D., Jang, H. I., Quilain, B., Intonti, RA, Nishimura, Y, Mine, S., Cowan, G, Redij, A, Cowan, G., Richard, E, Mori, T., Andreopoulos, C, Nicholls, T, Cremonesi, L., Pac, M. Y., Tacik, R, Wark, D., Jiang, M., Ma, W, Kishimoto, Y., Vogelaar, R. B., Catanesi, MG, Ikeda, M, Rott, C, Suzuki, Y., Scholberg, K, Haegel, L., Vasseur, G., Marti, L, Haegel, L, Yano, T., Ganezer, K., Oser, SM, Askins, M., Laveder, M, Himmel, A., Katori, T, Walter, CW, Back, J. J., Askins, M, Tolich, N, Shaikhiev, A., Berry, T., Bay, F., Kaboth, A, Martin, C, Rosa, G. De, Kameda, J., Weber, A, Pistillo, C., Ballett, P, Suzuki, A. T., Perevozchikov, O, Yanagisawa, C, Ballett, P., Noah, E, Wendell, R, Iijima, T, Ishitsuka, M., Suzuki, Y, Mazzucato, E., Blondel, A, Ishino, H, Okajima, Y, Koga, M., Wilson, JR, Ratoff, PN, Kuze, M., Lindner, T, Emery, S, Marti, L., Hayato, Y, Kutter, T, Hartfiel, B, Sekiya, H, Iijima, T., Xin, T., O'Keeffe, HM, Friend, M., Khotjantsev, A, Khabibullin, M, Nirkko, M, Nakayama, S., Yokoyama, M., Lawe, M, Ariga, A., Asfandiyarov, R, Friend, M, Gumplinger, P., Choi, K, Mahn, K., Hartz, M., Kobayashi, T, Nakahata, M, Ross-Lonergan, M., Bergevin, M., Choi, K., Aihara, H., Choi, JH, Nakaya, T., Tanaka, H. A., Inoue, K., Sekiya, H., Insler, J., Yokoyama, M, Bravar, A, Blaszczyk, F. d. M., Fernandez, P, Gumplinger, P +476 morecore YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura +2 morewiley +1 more sourceExploiting multi-word units in history-based probabilistic generation [PDF]
, 2007 We present a simple history-based model for sentence generation from LFG f-structures, which improves on the accuracy of previous models by breaking down PCFG independence assumptions so that more f-structure conditioning context is used in the ...Cahill, Aoife, Conor Cafferkey, Josef Van Genabith, Aoife Cahill, Deirdre Hogan, Hogan, Deirdre, van Genabith, Josef, Cafferkey, Conor +7 morecore MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov +7 morewiley +1 more sourceAccurate and robust LFG-based generation for Chinese [PDF]
, 2008 We describe three PCFG-based models for Chinese sentence realisation from Lexical-Functional Grammar (LFG) f-structures. Both the lexicalised model and the history-based model improve on the accuracy of a simple
wide-coverage PCFG model by adding ...Guo, Yuqing, Josef van Genabith, Yuqing Guo, Wang, Haifeng, van Genabith, Josef, Haifeng Wang +5 morecore +1 more source
