Results 151 to 160 of about 900,332 (265)

Esterified Cholesterol Conjugates Enable LNP‐Mediated mRNA Delivery to the Blood–Brain Barrier Following Intravenous Administration

Advanced Materials, EarlyView.
A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian, Xu Wang, Alexis Pacheco Benitez, Erick Guerrero, Yaou Duan, Jingwen Wei, Lukas Farbiak, Daniel J. Siegwart   +7 more
wiley   +1 more source

Nonlinear Association Between Serum Uric Acid and Incident Stroke in Patients with Diabetes: A Two-Centre Cohort Study. [PDF]

Int J Gen Med
Xu S, Yuan J, Guo Y, An K, Liu C, Wang H, Li M.   +6 more
europepmc   +1 more source

Bioengineered Interfaces for Peripheral Nerve Sensory Restoration

Advanced Materials, EarlyView.
Half of amputees abandon their prosthetics for lack of feeling. This review charts the full path from peripheral nerve injury to restored sensation, through surgical, regenerative, noninvasive, and implanted approaches, and shows how injury type and interface material properties determine which strategy can deliver naturalistic feedback, and why ...
Sydney Swedick, Salim El Hadwe, Kesi Liang, George G. Malliaras, Damiano G. Barone   +4 more
wiley   +1 more source

Fiber‐Format Flexible Linear Electrostatic Motors

Advanced Materials, EarlyView.
A flexible coaxial fibre‐format electrostatic motor enables backdrivable and reversible linear actuation with high force density and functionality under bending, offering a scalable actuation platform for soft and wearable robotics. ABSTRACT Linear motion is fundamental to robotics, yet existing solutions are either rigid electromagnetic motors or ...
Sylvain Schaller, Herbert Shea
wiley   +1 more source

Genetic Insights Into Protective Effects of GLP-1 Receptor Agonists on Stroke and Alzheimer Disease Across Ancestries. [PDF]

Neurol Genet
Caro-Châtelier I, Sargurupremraj M, Yang C, Akinleye C, Trégouët DA, Akinyemi RO, Shigemizu D, Coker M, Akinyemi JO, Tiwari HK, Chasman DI, Ovbiagele B, Chabriat H, Mooser V, Couffinhal T, Mishra A, Cruchaga C, Reitz C, Kunkle B, Kamatani Y, Owolabi MO, Mohammedi K, Debette S.   +22 more
europepmc   +1 more source

Microfabrication of Soft Millirobots Propelled by Low Voltage Electrohydraulic Actuators

Advanced Materials Technologies, EarlyView.
Manual layer‐by‐layer assembly is replaced by wafer‐level MEMS batch fabrication for compliant polymer‐based electrohydraulic actuators. The microfabricated devices integrate sacrificially defined microcavities, Parylene‐C‐sealed inlets, and multilayer polymer–metal films.
Shai Shmulevich, Florian Hartmann, Herbert Shea   +2 more
wiley   +1 more source

Unlocking Terahertz Steganography: Authentication of Hidden Images in Flexible Media

Advanced Materials Technologies, EarlyView.
Hidden information in multilayered devices, such as steganographic portraits, is detected and authenticated using reflection‐mode terahertz time‐domain imaging. Image reconstruction relies on a dedicated figure‐of‐merit obtained by integrating the signal intensity over the time‐window associated with the reflection from the metallic mirror backing the ...
Tiziana Ritacco, Francesca Vittorioso, Dimitrios C. Zografopoulos, Romeo Beccherelli, Walter Fuscaldo   +4 more
wiley   +1 more source