Results 91 to 100 of about 25,547,481 (294)
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
El debate sobre la duración del curso lectivo en las escuelas y colegios públicos, se ha empantanado. Ahora resulta que la gran cuestión a decidir es si el curso dura 200 o 174 días. ¡Cómo si esos fueran números mágicos!
Sonia Roblero Rodríguez
doaj
200 Countries and 200 Years in 4 Minutes
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openaire +1 more source
Published to accompany the exhibition held at 200 Gertrude Street, 1-23 November ...
200 Gertrude Street (Gallery)
core
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Darren Sylvester : life together.
Catalogue of an exhibition held at 200 Gertrude Street, Fitzroy, Vic., 6-28 Mar ...
200 Gertrude Street (Gallery)
core
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Profiling cells with DELs: Small molecule fingerprinting of cell surfaces
DNA-encoded small molecule library technology has recently emerged as a new paradigm for identifying ligands against drug targets. To date, it has been used to identify ligands against targets that are soluble or overexpressed on cell surfaces.
Jason Deng +14 more
doaj +1 more source
Catalogue for exhibition held Friday 2 March - Saturday 31 March, 1990 at 200 Gertrude ...
200 Gertrude Street (Gallery)
core
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source

