Results 111 to 120 of about 6,302,624 (294)

200 números de Proyección

Proyección, 2001
En mayo de 1954 salía a la luz el primer número de la revista Proyección. Este es el número 200, lo cual es motivo de alegría y de agradecimiento. A lo largo de casi cinco décadas nuestra revista ha realizado el programa que se asignó a sí misma en ...
Juan M. Rufo
doaj  

200 anos de caleidoscópio

Revista Brasileira de Ensino de Física
A UNESCO estabeleceu que 2015 foi o Ano Internacional da Luz (AIL), porém, em 2016, celebramos os 200 anos da invenção do caleidoscópio. Embora, nos dias de hoje, ele não atraia tanto interesse quanto na época da sua invenção, esse precioso instrumento ...
Rebeca Saldanha de Araújo Omelczuck, Diogo Soga, Mikiya Muramatsu   +2 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Unquenchable

, 1998
Catalogue of an exhibition held at 200 Gertrude Street, Fitzroy, Vic., 6-27 June 1998.Artist: Elisa ...
200 Gertrude Street (Gallery)
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Art for a future generation

, 1998
Published to accompany the exhibition held at 200 Gertrude Street, 8th-29th August ...
200 Gertrude Street (Gallery)
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Anne Connors : prints & drawings

, 1989
Catalogue of an exhibition held at 200 Gertrude Street, Fitzroy, Vic., 4 - 25 Feb ...
200 Gertrude Street (Gallery)
core  

MicroRNA-200 (miRNA-200) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source