Results 41 to 50 of about 3,811,869 (264)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
A gene catalogue of the amphioxus nervous system
The elaboration of extremely complex nervous systems is a major success of evolution. However, at the dawn of the post-genomic era, few data have helped yet to unravel how a nervous system develops and evolves to complexity.
Èlia Benito-Gutiérrez
doaj
Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines
mRNA vaccines have the potential to tackle many unmet medical needs that are unable to be addressed with conventional vaccine technologies. A potent and well-tolerated delivery technology is integral to fully realizing the potential of mRNA vaccines. Pre-
Kimberly J. Hassett +18 more
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Perturbation of external neutron source can cause significant local power changes transformed into undesired safety-related events in an accelerator driven system.
Stankovskiy Alexey +2 more
doaj +1 more source
Com a efeméride das comemorações de duzentos anos do nascimento de Karl Marx, o texto apresenta as quatro fases de sua trajetória enquanto jornalista e debate quais características desta práxis noticiosa podem ser relevantes para uma teoria da prática ...
Rafael Bellan Rodrigues de Souza
doaj +1 more source
DRONE BASED NEAR REAL-TIME HUMAN DETECTION WITH GEOGRAPHIC LOCALIZATION [PDF]
Detection of humans, e.g. for search and rescue operations has been enabled by the availability of compact, easy to use cameras and drones. On the other hand, aerial photogrammetry techniques for inspection applications allow for precise geographic ...
P. J. Baeck +4 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source

