Results 41 to 50 of about 6,302,624 (294)
A gene catalogue of the amphioxus nervous system
International Journal of Biological Sciences, 2006 The elaboration of extremely complex nervous systems is a major success of evolution. However, at the dawn of the post-genomic era, few data have helped yet to unravel how a nervous system develops and evolves to complexity.
Èlia Benito-Gutiérrez
doaj
Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines
Molecular Therapy: Nucleic Acids, 2019 mRNA vaccines have the potential to tackle many unmet medical needs that are unable to be addressed with conventional vaccine technologies. A potent and well-tolerated delivery technology is integral to fully realizing the potential of mRNA vaccines. Pre-
Kimberly J. Hassett +18 more
doaj +1 more source
200 years of the RAS: The first 200 Fellows
Astronomy & Geophysics, 2020 Abstract Mike Edmunds takes a look at members of the Society in the first years of its life and finds a familiar group: enthusiasts, scholars, men of industry, explorers and eccentrics.
openaire +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
EPJ Web of Conferences, 2017 Perturbation of external neutron source can cause significant local power changes transformed into undesired safety-related events in an accelerator driven system.
Stankovskiy Alexey +2 more
doaj +1 more source
Rumores, 2019 Com a efeméride das comemorações de duzentos anos do nascimento de Karl Marx, o texto apresenta as quatro fases de sua trajetória enquanto jornalista e debate quais características desta práxis noticiosa podem ser relevantes para uma teoria da prática ...
Rafael Bellan Rodrigues de Souza
doaj +1 more source
DRONE BASED NEAR REAL-TIME HUMAN DETECTION WITH GEOGRAPHIC LOCALIZATION [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2019 Detection of humans, e.g. for search and rescue operations has been enabled by the availability of compact, easy to use cameras and drones. On the other hand, aerial photogrammetry techniques for inspection applications allow for precise geographic ...
P. J. Baeck +4 more
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source