Results 31 to 40 of about 18,413,854 (345)
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Ministries Examined: Laity, Clergy, Women, and Bishops in a Time of Change [PDF]
, 1989 Reviewed Book: Reumann, John Henry Paul. Ministries Examined: Laity, Clergy, Women, and Bishops in a Time of Change.
Jacobson, J. Robert
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Revista de Historia, 2009 La historiografía costarricense no ha abordado aún suficientemente la problemática del desarrollo agrario regional. En este sentido, la obra de Antoni Royo representa un gran aporte para diversas ciencias y disciplinas. La formación del autor en diversos
Andrea Montero Mora
doaj
Publish-and-Flourish: Using Blockchain Platform to Enable Cooperative Scholarly Communication
Publications, 2019 Scholarly communication is today immersed in publish-or-perish culture that propels non-cooperative behavior in the sense of strategic games played by researchers.
Emilija Stojmenova Duh +6 more
doaj +1 more source
Applied Sciences, 2023 This research aims to determine whether a neural response telemetry (NRT) threshold determines the success of surgery. Furthermore, we examined whether the patient’s age, the etiology of their hearing loss, the depth of the electrode insertion, and a ...
Tina Gabrovec +4 more
doaj +1 more source
Educación, 2000 Se presenta un informe ejecutivo sobre el Plan Nacional de Capacitación Docente (PLANCAD) llevado a cabo por la Unifé, capacitando a 16 directores y 197 docentes de los Centros Educativos Estatales de los distritos de Surco y Los Olivos en Lima-Perú.
openaire +3 more sources
Thermodynamics Characterization of Density models for an Effective Solar Water Heater Sizing [PDF]
, 2012 The problem faced in Sizing of an effective Solar Water Heater (SWH) by engineers to meet certain design requirement is highly enormous. Using the thermodynamic characterization relation and the knowledge of Solar Water Heater (SWH) density’s model ...
Aasa, S. A. +2 more
core
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source