Results 41 to 50 of about 18,477,494 (319)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Representing Londinium: The Influence of Colonial and Post-Colonial Discourses 

Theoretical Roman Archaeology Journal, 2001
None
Francis Grew
doaj   +2 more sources

The development of mouthwashes without anti-gonococcal activity for controlled clinical trials: an in vitro study [version 2; peer review: 2 approved]

F1000Research, 2020
Background: The oropharynx plays a major role in the development and spread of antimicrobial resistant Neisseria gonorrhoeae among men who have sex with men.
Christophe Van Dijck, Vicky Cuylaerts, Piet Sollie, Anna Spychala, Irith De Baetselier, Jolein Laumen, Tania Crucitti, Chris Kenyon   +7 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Writing Colonial Conflict, Acknowledging Colonial Weakness

Theoretical Roman Archaeology Journal, 2001
None
Garrick Fincham
doaj   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Studi Implementasi Iso 9000 : 2000 pada Perusahaan Konstruksi di Makassar

Jurnal Teknik Sipil, 2010
Abstrak. Pengelolaan mutu yang sistematik dapat mengurangi biaya kegagalan produk dan jasa. Oleh karena itu diperlukan standar untuk melakukan pekerjaan yang efisien dengan menciptakan konsistensi mutu.
Muhammad Sapri Pamulu, Muhammad Salsabil Husni   +1 more
doaj  

An Archaeology of Food: A Case Study From Roman Britain

Theoretical Roman Archaeology Journal, 2001
None
Gillian Hawkes
doaj   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Editorial introduction [to Strategic uncertainties: ethics, politics and risk in contemporary educational research] [PDF]

, 2004
Strategic Uncertainties: Ethics, Politics and Risk in Contemporary Educational Research offers new perspectives on contemporary educational research in a wide range of contexts and settings.
Coombes, Phyllida, Danaher, Mike, Danaher, Patrick Alan   +2 more
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