Results 31 to 40 of about 5,028,694 (249)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Mortalidad infantil y marginación en la península de Yucatán
Se presentan resultados de un estudio orientado a conocer la distribución territorial de la mortalidad infantil y su relación con algunos indicadores socioeconómicos en la península de Yucatán, en el período 1990-2000.
Rosa María Méndez González +2 more
doaj
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Guía administrativa para implementar el sistema de gestión de calidad
El propósito de este artículo es analizar aspectos administrativos de organizaciones boyacenses y crear una guía para orientar al pequeño y mediano empresario en la implementación del Sistema de Gestión de Calidad (SGC).
Ana Mercedes Fraile Benítez
doaj
Animal Iconographies: Metaphor, Meaning and Identity (or Why Chinese Dragons Don’t Have Wings)
None
Miranda J. Aldhouse Green
doaj +2 more sources
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Medicine, Culture and Military Identity
None
Patricia A. Barker
doaj +2 more sources
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Unpicking a Myth: The Infanticide of Female and Disabled Infants in Antiquity
None
Eleanor Scott
doaj +2 more sources
Background: The oropharynx plays a major role in the development and spread of antimicrobial resistant Neisseria gonorrhoeae among men who have sex with men.
Christophe Van Dijck +7 more
doaj +1 more source

