Results 31 to 40 of about 18,261,697 (295)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Indice

Studi di Storia Medioevale e di Diplomatica: Nuova Serie, 2018
Indice del diciottesimo numero della ...
SSMD 2000
doaj  

Patrick Ledderose: Dramatische Zeiten. Zeitkonzepte in skandinavischen Theatertexten um 1900 und 2000. Nordica, Band 28. Baden- Baden: Rombach Wissenschaft 2021, 391 S. [PDF]

NORDEUROPAforum - Zeitschrift für Kulturstudien, 2023
Knut Ove Arntzen
doaj   +1 more source

Should We ‘Eat a Rainbow’? An Umbrella Review of the Health Effects of Colorful Bioactive Pigments in Fruits and Vegetables

Molecules, 2022
Health promotion campaigns have advocated for individuals to ‘eat a rainbow’ of fruits and vegetables (FV). However, the literature has only focused on individual color pigments or individual health outcomes. This umbrella review synthesized the evidence
Michelle Blumfield, Hannah Mayr, Nienke De Vlieger, Kylie Abbott, Carlene Starck, Flavia Fayet-Moore, Skye Marshall   +6 more
doaj   +1 more source

Back Cover [PDF]

, 1976
Back cover of this ...

core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Publish-and-Flourish: Using Blockchain Platform to Enable Cooperative Scholarly Communication

Publications, 2019
Scholarly communication is today immersed in publish-or-perish culture that propels non-cooperative behavior in the sense of strategic games played by researchers.
Emilija Stojmenova Duh, Andrej Duh, Uroš Droftina, Tim Kos, Urban Duh, Tanja Simonič Korošak, Dean Korošak   +6 more
doaj   +1 more source

Comparison of Perioperative Electrophysiological Measurements and Postoperative Results in Cochlear Implantation with a Slim Straight Electrode

Applied Sciences, 2023
This research aims to determine whether a neural response telemetry (NRT) threshold determines the success of surgery. Furthermore, we examined whether the patient’s age, the etiology of their hearing loss, the depth of the electrode insertion, and a ...
Tina Gabrovec, Jana Dragar, Domen Guzelj, Petra Povalej Bržan, Janez Rebol   +4 more
doaj   +1 more source

PLANCAD 2000

Educación, 2000
Se presenta un informe ejecutivo sobre el Plan Nacional de Capacitación Docente (PLANCAD) llevado a cabo por la Unifé, capacitando a 16 directores y 197 docentes de los Centros Educativos Estatales de los distritos de Surco y Los Olivos en Lima-Perú.
openaire   +3 more sources