Results 31 to 40 of about 5,028,694 (249)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Mortalidad infantil y marginación en la península de Yucatán

open access: yesInvestigaciones Geográficas, 2004
Se presentan resultados de un estudio orientado a conocer la distribución territorial de la mortalidad infantil y su relación con algunos indicadores socioeconómicos en la península de Yucatán, en el período 1990-2000.
Rosa María Méndez González   +2 more
doaj  

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Guía administrativa para implementar el sistema de gestión de calidad

open access: yesSemestre Económico, 2007
El propósito de este artículo es analizar aspectos administrativos de organizaciones boyacenses y crear una guía para orientar al pequeño y mediano empresario en la implementación del Sistema de Gestión de Calidad (SGC).
Ana Mercedes Fraile Benítez
doaj  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Medicine, Culture and Military Identity

open access: yesTheoretical Roman Archaeology Journal, 2001
None
Patricia A. Barker
doaj   +2 more sources

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

The development of mouthwashes without anti-gonococcal activity for controlled clinical trials: an in vitro study [version 2; peer review: 2 approved]

open access: yesF1000Research, 2020
Background: The oropharynx plays a major role in the development and spread of antimicrobial resistant Neisseria gonorrhoeae among men who have sex with men.
Christophe Van Dijck   +7 more
doaj   +1 more source

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