Results 71 to 80 of about 5,028,694 (249)

The grandstands at the archery venue, Sydney 2000 Olympic Games, 21 September 2000 [picture] /

, 2000
Title from the descriptive list.; Part of collection: Hockey, archery and fencing events, Sydney 2000 Olympic Games, 21 September ...
Seselja, Loui, 1948-
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

The development of mouthwashes without anti-gonococcal activity for controlled clinical trials: an in vitro study [version 1; peer review: 2 approved]

F1000Research, 2019
Background: The oropharynx plays a major role in the development and spread of antimicrobial resistant Neisseria gonorrhoeae among men who have sex with men.
Christophe Van Dijck, Vicky Cuylaerts, Piet Sollie, Anna Spychala, Irith De Baetselier, Jolein Laumen, Tania Crucitti, Chris Kenyon   +7 more
doaj   +1 more source

Men's high jump, Sydney 2000 Olympic Games, 24 September 2000 [2] [picture] /

, 2000
Title from the descriptive list.; Marathon, sailing and athletics events, Sydney 2000 Olympic Games, 24 September ...
Seselja, Loui, 1948-
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Left Atrial Volume Index Predicts Atrial Fibrillation Recurrence after Catheter Ablation Only in Obese Patients—Brief Report

Diagnostics
Background: It has been shown that obesity and a higher body mass index (BMI) are associated with a higher recurrence rate of atrial fibrillation (AF) after successful catheter ablation (CA).
Franjo Husam Naji, Jan Alatic, Igor Balevski, David Suran   +3 more
doaj   +1 more source

Spectators, men's rowing, Penrith Lakes, Sydney 2000 Olympic Games, 23 September 2000 [1] [picture] /

, 2000
Title from the descriptive list.; Part of collection: Mountain bike riding, rowing and football events, Sydney 2000 Olympic Games, 23 September ...
Seselja, Loui, 1948-
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

The song of the Brazilian population of Humpback Whale Megaptera novaeangliae, in the year 2000: individual song variations and possible implications

Anais da Academia Brasileira de Ciências, 2004
The song of the Brazilian population of the Humpback Whale Megaptera novaeangliae was studied in its breeding and calving ground, the Abrolhos Bank, Bahia, Brazil, from July to November 2000.
Arraut Eduardo M., Vielliard Jacques M.E.   +1 more
doaj  

Official merchandise tent, Sydney 2000 Olympic Games, 20 September 2000 [picture] /

, 2000
Title from the descriptive list.; Part of collection: Badminton, table tennis, basketball and baseball events, Sydney 2000 Olympic Games, 20 September ...
Seselja, Loui, 1948-
core