Results 31 to 40 of about 5,298,705 (317)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Health expenditure Australia 2013–14 [PDF]
, 2015 This report includes estimates of how much was spent on health between 2003–04 and 2013–14. This information contributes to understanding the performance and efficiency of Australia’s health system and how changes arise over time.
Australian Institute of Health and Welfare
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Le elezioni nel mondo – Luglio-Dicembre 2013
QOE-IJES, 2014 Europa: Austria, Georgia, Germania, Lussemburgo, Norvegia, Repubblica Ceca; Africa: Mali; Americhe: Argentina, Cile, Honduras; Asia: Giappone; Oceania: Australia.
SIlvia Bolgherini
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Aboriginal and Torres Strait Islander health organisations: online services report - key results 2013-14 [PDF]
, 2015 This sixth national report provides an overview of 269 Australian Government-funded organisations that aim to improve the health of Aboriginal and Torres Strait Islander people. It presents findings from the 2013-14 Online Services Report data collection,
Australian Institute of Health and Welfare
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The Malaysian General Elections of 2013: The Last Attempt at Secular-inclusive Nation-building?
Journal of Current Southeast Asian Affairs, 2013 This paper looks at the Malaysian General Election campaign of 2013, and focuses primarily on the 1Malaysia project that was foregrounded by the administration of Prime Minister Najib Razak.
Farish A. Noor
doaj
Editorial. Psychology in Russia: State of the Art [PDF]
Psychology in Russia: State of Art, 2013 This issue is dedicated to the 80th anniversary of O.K. Tikhomirov’s birth (1933 —2001). O.K. Tikhomirov was a professor of psychology at Lomonosov Moscow State University.
Zinchenko, Yury P.
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
OECD health-care quality indicators for Australia 2011-12 [PDF]
, 2014 This report summarises information Australia provided in 2013 to the Organisation for Economic Co-operation and Development’s Health Care Quality Indicators 2012–13 data collection.
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Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source