Results 41 to 50 of about 23,392,444 (312)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Linfieldpdx, 2013 [PDF]

, 2013
Linfieldpdx, an annual newsletter for Linfield College\u27s nursing and health sciences alumni and friends, features stories about alumni, the campus, and programs. Included in this issue: a column from the interim dean Lloydena V. Grimes Award exhibit
Davis, Laura, Mileham, Mardi
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

IMPACT, Fall 2013 [PDF]

, 2013
https://scholarworks.sjsu.edu/impact/1002/thumbnail ...
San Jose State University, Connie L. Lurie College of Education
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

O Brasil no mundo de 2013 [PDF]

Psicologia USP
Resumo: As Jornadas de Junho de 2013 têm sido tema de inúmeras discussões no âmbito da psicologia social, da sociologia e da ciência política e constituem um importante analisador das vicissitudes do sistema democrático no Brasil. Este ensaio consiste em
Fabio Dal Molin
doaj   +1 more source

Editorial. Psychology in Russia: State of the Art [PDF]

Psychology in Russia: State of Art, 2013
This issue is dedicated to the 80th anniversary of O.K. Tikhomirov’s birth (1933 —2001). O.K. Tikhomirov was a professor of psychology at Lomonosov Moscow State University.
Zinchenko, Yury P.
doaj   +1 more source

Communicator, April. 2013 [PDF]

, 2013
Volume 25, Issue
San Jose State University, Department of Kinesiology
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

The Malaysian General Elections of 2013: The Last Attempt at Secular-inclusive Nation-building?

Journal of Current Southeast Asian Affairs, 2013
This paper looks at the Malaysian General Election campaign of 2013, and focuses primarily on the 1Malaysia project that was foregrounded by the administration of Prime Minister Najib Razak.
Farish A. Noor
doaj