Results 41 to 50 of about 3,072,077 (242)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

O Festival Internacional de Teatro de Almada: uma organização de diversidade única

open access: yesSinais de Cena, 2014
O Festival Internacional de Teatro de Almada: uma organização de diversidade ...
João Carneiro
doaj  

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks   +10 more
wiley   +1 more source

A luva virada do avesso

open access: yesSinais de Cena, 2013
Crítica ao espectáculo Por tudo e por nada de Nathalie Sarraute, encenacão de Jorge Silva Melo, Artistas Unidos, Teatro da Politécnica, 2013. 
Emília Costa
doaj  

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund   +3 more
wiley   +1 more source

Parental Perception and Practices Relating to Parent-Child Communication on Sexuality in Lagos, Nigeria

open access: yesJournal of Family and Reproductive Health, 2009
Objective: This study aimed at contributing to the promotion of positive communication between parents and children in order to help the children establish individual values and make sexually healthy decisions.
Olaoluwa Akinwale   +7 more
doaj  

O Brasil no mundo de 2013 [PDF]

open access: yesPsicologia USP
Resumo: As Jornadas de Junho de 2013 têm sido tema de inúmeras discussões no âmbito da psicologia social, da sociologia e da ciência política e constituem um importante analisador das vicissitudes do sistema democrático no Brasil. Este ensaio consiste em
Fabio Dal Molin
doaj   +1 more source

Acknowledgements 2013 / Remerciements 2013

open access: yes, 2014
Éditoral ...
Williams-Jones, Bryn   +3 more
openaire   +1 more source

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