Results 21 to 30 of about 5,705,295 (290)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Displace Altofest [PDF]

open access: yes, 2018
In this essay, the focus will be on how the meanings of space and place played out in Altofest Malta 2018. Lefebvre (1991: 26) underlines that space is a concept; it is also a physical and material space.
Valletta 2018 Foundation   +1 more
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Disability support services strategic plan 2014 to 2018 [PDF]

open access: yes, 2015
The Ministry of Health’s Disability Support Services (DSS) group has developed a four-year Strategic Plan for 2014 to 2018. Summary The plan sets out the vision for Disability Support Services – that disabled people and their families are ...
Ministry of Health (New Zealand)
core  

Selected Abstracts of the 2nd International Workshop “Intensive Care of the Newborn”; Verona (Italy); March 9-10, 2018 – Erratum

open access: yesJournal of Pediatric and Neonatal Individualized Medicine, 2018
This is an erratum to: Selected Abstracts of the 2nd International Workshop “Intensive Care of the Newborn”; Verona (Italy); March 9-10, 2018. J Pediatr Neonat Individual Med. 2018;7(1):e070125. doi: 10.7363/070125.
--- Various Authors
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Population balance modelling of bubble columns under the heterogeneous regime [PDF]

open access: yes, 2018
Population Balance Modeling Conference 2018 (PBM ...
Marchisio Daniele   +7 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Tobacco indicators baseline data: reporting under the National Tobacco Strategy 2012–2018 [PDF]

open access: yes, 2015
Overview This report presents baseline data for the outcome indicators listed under Part Seven of the National Tobacco Strategy (NTS) 2012-2018, and for an additional 6 indicators that were agreed to when the reporting framework was developed (see ...
Australian Institute of Health and Welfare
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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