Results 21 to 30 of about 21,884,175 (311)

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

Le juge judiciaire et le secret des affaires

open access: yesDroit et Cultures, 2023
In view of an interdisciplinary research on “justice and secrecy”, the purpose of the study is the judicial treatment of the trade secrets, born from practice and often invoked in courtrooms.
Aurélie Ballot-Léna
doaj   +1 more source

The Implications of New Historicism for Evangelical Bible Interpretation: An Evaluation [PDF]

open access: yes, 2020
The twentieth century has seen a rise in recognizing the Bible not only as historical or theological work but also as a piece of literature, and the natural progression of this idea is to apply the same methods used for literary texts to the biblical ...
DeOrnellis, Drake
core   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai   +4 more
wiley   +1 more source

Selected Abstracts of the 2nd International Workshop “Intensive Care of the Newborn”; Verona (Italy); March 9-10, 2018 – Erratum

open access: yesJournal of Pediatric and Neonatal Individualized Medicine, 2018
This is an erratum to: Selected Abstracts of the 2nd International Workshop “Intensive Care of the Newborn”; Verona (Italy); March 9-10, 2018. J Pediatr Neonat Individual Med. 2018;7(1):e070125. doi: 10.7363/070125.
--- Various Authors
doaj   +1 more source

What Were They Thinking? Insider Trading and the Scienter Requirement [PDF]

open access: yes, 2012
On its face, the connection between insider trading regulation and the state of mind of the trader or tipper seems intuitive. Insider trading is a form of market abuse: taking advantage of a secret to which one is not entitled, generally in breach of ...
Langevoort, Donald C
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

A Novel Application of B.EL.D™ Technology: Biosensor-Based Detection of Salmonella spp. in Food

open access: yesBiosensors
The prevalence of foodborne diseases is continuously increasing, causing numerous hospitalizations and deaths, as well as money loss in the agri-food sector and food supply chain worldwide. The standard analyses currently used for bacteria detection have
Lazaros Konstantinou   +6 more
doaj   +1 more source

Analysis of Surface Collections from Areas A and B at the Sam Roberts Site (41CP8) on Prairie Creek, Camp County, Texas [PDF]

open access: yes, 2013
The Sam Roberts site is a large ancestral Caddo mound center and habitation site on the floodplain of Prairie Creek, an eastward-flowing tributary to Big Cypress Creek, as well as on an upland landform south of the creek. Robert L.
Perttula, Timothy K.
core   +1 more source

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