Results 31 to 40 of about 6,995,818 (277)
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
65.º Aniversario del Hospital de Clínicas. Semana Académica 2018
Anales de la Facultad de Medicina, 2019 Este año, la tradicional Semana Académica del Hospital de Clínicas de la Facultad de Medicina de la Universidad de la República, Uruguay, tuvo lugar del 17 al 21 de setiembre.
Equipo Editor
doaj
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
, 2019 Nominata referente ao volume 8 (2018) da revista Cadernos CIMEAC. A revista agradece a contribuição dos(as) pesquisadores(as) e docentes relacionados para a manutenção da qualidade científica e editorial do ...
2018, Nominata de
core +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Second EOSCpilot Stakeholders Forum (Wien, 21.–22. November 2018)
Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare, 2019 Bericht vom letzten “EOSCpilot Stakeholders Forum”, 21. und 22. November 2018 im Austria Center in Wien. Einen Tag vor dem Launch der “European Open Science Cloud” (EOSC) unter österreichischer EU-Ratspräsidentschaft wurde hier vorgestellt, wie weit die ...
Thomas Haselwanter
doaj +1 more source
Earth's Future, 2020 The mechanisms causing European heatwaves in recent years, particularly their differences among several heatwaves, are poorly understood. Here atmospheric circulation anomalies and soil moisture‐temperature coupling during the summer 2018 heatwave are ...
Xuebang Liu +4 more
doaj +1 more source
Novelties in imaging in pulmonary fibrosis and nodules. A narrative review
Pulmonology, 2020 In recent months two major fields of interest in pulmonary imaging have stood out: pulmonary fibrosis and pulmonary nodules. New guidelines have been released to define pulmonary fibrosis and subsequent studies have proved the value of these changes.
S. Ley, J. Ley-Zaporozhan
doaj +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source