Results 31 to 40 of about 5,705,295 (290)
Commonwealth Games: friendly rivalry [PDF]
, 2013 This paper looks back at how the Commonwealth Games came to be, Australia’s experience of staging the event and contemplates how the Gold Coast will deal with that legacy and surmount perceived and unexpected complications that will inevitably surface
Rhonda Jolly
core
A Novel Application of B.EL.D™ Technology: Biosensor-Based Detection of Salmonella spp. in Food
BiosensorsThe prevalence of foodborne diseases is continuously increasing, causing numerous hospitalizations and deaths, as well as money loss in the agri-food sector and food supply chain worldwide. The standard analyses currently used for bacteria detection have
Lazaros Konstantinou +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Resolución CDEyVE SAVyVM N° 10/2018. Rectificar la Resolución CDEyVE SAVyVM Nº 05/2018. [PDF]
, 2018 Fil: Consejo de Docencia, Extensión y Vida Estudiantil de Sede Alto Valle y Valle Medio (CD). Universidad Nacional de Río Negro. Río Negro, ArgentinaResolución CDEyVE SAVyVM N° 10/2018.
Consejo de Docencia, Extensión y Vida Estudiantil de Sede Alto Valle y Valle Medio (CD)
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
65.º Aniversario del Hospital de Clínicas. Semana Académica 2018
Anales de la Facultad de Medicina, 2019 Este año, la tradicional Semana Académica del Hospital de Clínicas de la Facultad de Medicina de la Universidad de la República, Uruguay, tuvo lugar del 17 al 21 de setiembre.
Equipo Editor
doaj
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source