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In December 2019, a new type viral pneumonia cases occurred in Wuhan, Hubei Province; and then named “2019 novel coronavirus (2019-nCoV)” by the World Health Organization (WHO) on 12 January 2020.
Ying-Hui Jin +46 more
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2019 novel coronavirus of pneumonia in Wuhan, China: emerging attack and management strategies
An ongoing outbreak of 2019-nCoV pneumonia was first identified in Wuhan, Hubei province, China at the end of 2019. With the spread of the new coronavirus accelerating, person-to-person transmission in family homes or hospitals, and intercity spread of ...
Jun She +5 more
doaj +1 more source
Molecular Insights into the Contagious Nature of Pandemic Novel Coronavirus 2019-nCoV
This article stems from the author's observations that ORF10, a protein with no sequence and structural conservation, provides with a high number of potentially immunogenic, promiscuous epitopes.
Seema Mishra (8621172)
core +1 more source
2019-nCoV – Towards a 4th generation vaccine [PDF]
The first report of the unusual manifestation of pneumonia-like symptoms in Wuhan City, China was made on 31 December 2019. Within one week, the Chinese authorities reported that they had identified the causative agent as a new member of the Coronavirus family, the same family of that was responsible for MERS and SARS not so many years ago.
openaire +2 more sources
Advances in research on ACE2 as a receptor for 2019-nCoV [PDF]
Currently, a novel coronavirus (SARS-CoV-2, also called 2019-nCoV) has triggered pandemic Coronavirus Disease 2019 (COVID-19), an acute infectious respiratory disease that first became epidemic in Wuhan (China) and is now spreading worldwide. Although 2019-nCoV and SARS-CoV are very similar viruses genomically and structurally, the huge number of ...
Wu, Jie +3 more
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Recently, news broke of the death of a young ophthalmologist named Li Wenliang at Wuhan Central Hospital in China, after being exposed to a patient who consulted him for glaucoma but was infected with coronavirus. The ophthalmologist, who appeared to be healthy, contracted coronavirus (2019-nCoV) and died a month after treating a simple red eye ...
Víctor Eduardo Reviglio +5 more
openaire +1 more source
With the current trajectory of the 2019-nCoV outbreak unknown, public health and medicinal measures will both be needed to contain spreading of the virus and to optimize patient outcomes.
Jared S. Morse (8279574) +3 more
core +1 more source
In silico identification of vaccine targets for 2019-nCoV [version 1; peer review: 2 approved]
Background: The newly identified coronavirus known as 2019-nCoV has posed a serious global health threat. According to the latest report (18-February-2020), it has infected more than 72,000 people globally and led to deaths of more than 1,016 people in ...
Chloe Hyun-Jung Lee, Hashem Koohy
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Novel Dynamic Structures of 2019-nCoV with Nonlocal Operator via Powerful Computational Technique
In this study, we investigate the infection system of the novel coronavirus (2019-nCoV) with a nonlocal operator defined in the Caputo sense. With the help of the fractional natural decomposition method (FNDM), which is based on the Adomian decomposition
Wei Gao +3 more
doaj +1 more source
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li +19 more
wiley +1 more source

