Results 61 to 70 of about 5,416,305 (343)
Journal of Pediatric and Neonatal Individualized Medicine, 2019 Lectures of the Nobel Week 2019 organized at Villa Nobel in Sanremo, Italy THE NEWS OF SCIENCE FOR A SUSTAINABLE FUTURE [LE NOVITÀ DELLA SCIENZA PER UN FUTURO SOSTENIBILE] Villa Nobel • Sanremo (Italy) • December 11th, 2019 The meeting has been ...
--- Various Authors
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Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Prime Minister Modi Returns, 2019: New Governance Agenda
Space and Culture, India, 2019 This editorial reviews the historic mandate of India's General Election of 2019, preceding nasty campaigns and futurist agenda for Mr Modi's second term.
Rituparna Bhattacharyya, Venkat Pulla
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
مجلة حوليات التراث العدد 19 [PDF]
Annales du Patrimoine, 2019 مجلة حوليات التراث، كلية الآدب والفنون، جامعة مستغانم، الجزائر، العدد 19 ...
د. محمد عباسة
doaj
Detection of Crimean Congo haemorrhagic fever virus in North-eastern Senegal, Bokidiawé 2019
Emerging Microbes and Infections, 2020 We diagnosed a human case of Crimean Congo hemorrhagic fever (CCHF) in Bokidiawe (North-eastern Senegal), 2019. The phylogenetic analysis revealed that the isolate belongs to genotype III and is closely related to a strain reported in Mauritania in 1984 ...
Idrissa Dieng +13 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
American Society of Hematology 2019 guidelines for immune thrombocytopenia.
Blood Advances, 2019 BACKGROUND Despite an increase in the number of therapies available to treat patients with immune thrombocytopenia (ITP), there are minimal data from randomized trials to assist physicians with the management of patients. OBJECTIVE These evidence-based
C. Neunert +16 more
semanticscholar +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Thromboinflammatory state and venous thromboembolic events in patients with coronavirus disease 2019 admitted to a non-intensive care ward: a prospective study [PDF]
, 2020 Alberto Fortini +5 more
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