Results 71 to 80 of about 21,259,860 (282)

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Two Economists, Three Opinions? Economic Models for Private International Law - Cross Border Torts as Example [PDF]

open access: yes, 2006
Many agree that private international law does a poor job of leading to good and predictable results. Can law and economics bring more scientific, objective foundations to the discipline? Economics, one may hope, can bring the conclusiveness to the field
Michaels, Ralf
core   +1 more source

ANALISIS PRODUKSI SUSU SAPI PERAH DI INDONESIA [PDF]

open access: yes, 2023
Cow's milk is large in contributing to meeting the needs of people in developing countries to meet nutritional fulfillment. Cow's milk has increased imports due to the problem of cow disease which cannot meet the needs of the Indonesian people who ...
Khairunnisa, Yanita Melga Fitria
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Editorial 2021 [PDF]

open access: yesMolecular Ecology Resources, 2020
Shawn Narum   +6 more
openaire   +2 more sources

A Neural-CBR System for Real Property Valuation [PDF]

open access: yes, 2013
In recent times, the application of artificial intelligence (AI) techniques for real property valuation has been on the increase. Some expert systems that leveraged on machine intelligence concepts include rule-based reasoning, case-based reasoning and
Daramola, Olawande   +3 more
core  

KIC 8462852: Will the Trojans return in 2021?

open access: yes, 2017
KIC 8462852 stood out among more than 100,000 stars in the Kepler catalogue because of the strange features of its light curve: a wide, asymmetric dimming taking up to 15 per cent of the light at D793 and a period of multiple, narrow dimmings happening ...
Arnalte-Mur, Pablo   +3 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

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