Results 91 to 100 of about 5,796,601 (292)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
, 2021 Fil: Consejo Superior de Programación y Gestión Estratégica (P). Universidad Nacional de Río Negro. Río Negro, ArgentinaResolución CSPyGE N° 18/2021. Derogar la Resolución CSPyGE N° 97/2019 y su modificatoria, Resolución CSPyGE N° 02/2021.
Consejo Superior de Programación y Gestión Estratégica (P)
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Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
International painting competition exibition „Marina 2021" : „Me and sea"
, 2021 Eksponuota „Vandens iliuzija“ (drobė/akrilas)Parodos vieta ir laikas: Jūrmalos miesto muziejus, Latvija, 2021 m. liepos 9 d. - rugpjjūčio 29 d.Vytauto Didžiojo universitetas / Vytautas Magnus UniversityŠvietimo akademija / Education AcademyMokytojų ...
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source