Results 41 to 50 of about 4,869,221 (316)
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Preface to the special issues of the International Conference on Ocean Energy 2024
The International Conference on Ocean Energy (ICOE) 2024 marked a significant milestone in the event’s history, taking place in Melbourne, Australia, from September 16–18, 2024.
Irene Penesis, Christophe Gaudin
doaj +1 more source
Predicting fatigue crack growth rate in a welded butt joint: The role of effective R ratio in accounting for residual stress effect [PDF]
A simple and efficient method is presented in this paper for predicting fatigue crack growth rate in welded butt joints. Three well-known empirical crack growth laws are employed using the material constants that were obtained from the base material ...
Servetti, Guido, Zhang, X.
core +1 more source
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Objetivo: analisar a produção científica nacional e internacional sobre a velocidade da marcha associada aos sinais, sintomas e fatores clínicos em pessoas idosas da atenção primária à saúde. Método: revisão integrativa de literatura realizada em cinco
Midiã Vanessa dos Santos Spekalski +6 more
doaj +1 more source
Detailed program of the TeaP 2024 conference in ...
University of Regensburg. Department of Psychology. Teap 2024 Organizing Team
core +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
A lo largo de la presente sección presentamos una síntesis de la jurisprudencia casacional sobre empleo público más significativa durante el primer período del año 2024.
José Ramón Chaves García +1 more
doaj +1 more source

