Results 111 to 120 of about 2,511,182 (316)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Prezentacja Inauguracyjna Roku Akademickiego 2025/2026 [PDF]

open access: yes
9 października 2025 roku w Centrum Kongresowym Uniwersytetu Przyrodniczego w Lublinie odbyła się uroczysta – w roku obchodów Jubileuszu 70-lecia – Inauguracja Roku Akademickiego 2025/2026. W wydarzeniu licznie uczestniczyli przedstawiciele władz Uczelni,
Uroczysta Inauguracja Roku Akademickiego 2025/2026 z okazji Jubileuszu 70-lecia Uniwersytetu   +1 more
core  

Spanish Cooperation’s Humanitarian Action Strategy 2019-2026 [PDF]

open access: yes, 2019
Bibliografía: p. 71-76En la nueva Estrategia humanitaria 2019-2026, renovada con un enfoque multilateralista y europeísta, se han reforzado aspectos clave del Grand Bargain como la resiliencia y nexo humanitario-desarrollo, la localización o las ...
Instituto de Estudios sobre Conflictos y Acción Humanitaria   +2 more
core   +1 more source

XLII Всероссийское диалектологическое совещание «Лексический атлас русских народных говоров – 2026»

open access: yesСлавянский альманах
26–27 января 2026 г. в Санкт-Петербургском отделении РАН прошло ежегодное Всероссийское диалектологическое совещание «Лексический атлас русских народных говоров – 2026». Текст поступил в редакцию 01.02.2026. Цитирование Шалаева Т. В. XLII Всероссийское
Татьяна Владимировна Шалаева
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Utility of MR spectroscopy and MR perfusion in characterizing intracranial pathology in Erdheim-Chester disease: A case report

open access: yesRadiology Case Reports
This case report describes the potential utility of MR spectroscopy and MR perfusion imaging in a patient with central nervous system involvement of Erdheim-Chester disease (ECD).
Momin Muzaffar, MD   +1 more
doaj   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Busia County Annual Development Plan 2025/2026 [PDF]

open access: yes
TI1e Busia County Annual Development Flan ( DF) for the fiscal Year 2025/2026 outlines the strategic framework for advancing sustainable socio-ecor,omic growth and development priorities in li11e ,,;th the development agenda espouc;ed in the Ru ia County
County Government of Busia
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

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