Results 161 to 170 of about 405,932 (228)

Efficacy of tocilizumab monotherapy after ultrashort glucocorticoid administration to treat giant cell arteritis: three-year follow-up. [PDF]

Rheumatology (Oxford)
Christ L, Seitz L, Scholz G, Bütikofer L, Kollert F, Reichenbach S, Villiger PM.   +6 more
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Characterization of bronchiectasis in lung cancer using German claims data. [PDF]

Sci Rep
Götschke J, Walter J, Kahnert K, Götschke M, Kapellos TS, Kauffmann-Guerrero D, Behr J, Tufman A, Mertsch P.   +8 more
europepmc   +1 more source

Metarhizium anisopliae Mitigates the Phytotoxicity of Lead and Nanoplastics on Rice by Modifying Physiological, Transcriptomic, Metabolomic Activities, and Soil Microbiome

Advanced Science, EarlyView.
Metarhizium anisopliae alleviates the phytotoxic effects of polyethylene nanoplastics (NP) and lead (Pb) in rice by decreasing Pb uptake, restoring antioxidant and hormonal equilibrium, and promoting growth. Additionally, the fungus modifies the rhizosphere microbiota, enhancing both contaminant tolerance and plant growth, thereby effectively ...
Jing Peng, Qi Yan, Muhammad Umair Hassan, Muhammad Imran, Fasih Ullah Haider, Jianfeng Liang, Xingmin Wang, Shaukat Ali   +7 more
wiley   +1 more source

Approaching Scarless Wound Healing: From Passive Anti‐Fibrotic to Proactive and Programmable Pro‐Regenerative Strategies

Advanced Science, EarlyView.
This review outlines the wound healing process and factors influencing scar formation, explores how certain animals and human fetuses achieve scarless skin or tissue regeneration, and details tissue engineering material strategies employed in scarless wound dressings.
Meimei Fu, Zhuoyi Huang, Jintao Li, Yue Li, Zhou Fang, Yiwen Jiang, Keke Wu, Jinshan Guo   +7 more
wiley   +1 more source

Correction: Progress in the discovery and development of anticancer agents from marine cyanobacteria.

Nat Prod Rep
Luesch H, Ellis EK, Chen QY, Ratnayake R.   +3 more
europepmc   +1 more source

Response to the letter to the editor: Clarifying NSQIP follow-up and estimated perioperative outcomes in lumbar decompression with or without fusion. [PDF]

Asian Spine J
Sharma A, Birring P, Acharya N, Mehta M, Goldenhersh NL, Steinhaus M, Wu HH, Hashmi S, Park DY, Lee YP, Bhatia N.   +10 more
europepmc   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

Advanced Science, EarlyView.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar, Jingwei Xie   +4 more
wiley   +1 more source

Quality of life and associated determinants of chronic pain among patients attending a primary healthcare clinic in Gqeberha: A cross-sectional study. [PDF]

S Afr Fam Pract (2004)
Dele-Ijagbulu KD, Ajudua FI, Cawe B.
europepmc   +1 more source